KEGG   DRUG: OlprinoneHelp
Entry
D08294                      Drug                                   

Name
Olprinone (INN)
Formula
C14H10N4O
Exact mass
250.0855
Mol weight
250.2554
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01757  Amrinone type cardiotonic
 DG01507  Phosphodiesterase III inhibitor
  DG01757  Amrinone type cardiotonic
Remark
Chemical group: 
Activity
Cardiotonic, Phosphodiesterase inhibitor
Comment
Amrinone derivative
Target
phosphodiesterase III [HSA:5139 5140] [KO:K19021 K13296]
  Pathway
Purine metabolism
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   phosphodiesterase (PDE) III
    Olprinone
     D08294  Olprinone (INN)
BRITE hierarchy
Other DBs
CAS: 
106730-54-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C8y C    20.9300  -17.6400
            2   C8y C    20.9300  -19.0400
            3   N4x N    22.1200  -19.7400
            4   C8y C    23.3100  -19.0400
            5   C8y C    23.3100  -17.6400
            6   C8x C    22.1200  -16.9400
            7   O5x O    19.6700  -19.7400
            8   C1a C    24.5700  -19.7400
            9   C3b C    19.6700  -16.9400
            10  N3a N    18.4800  -16.2400
            11  C8y C    24.5700  -16.9400
            12  C8x C    25.7600  -17.6400
            13  N4y N    26.9500  -16.9400
            14  C8y C    26.9500  -15.5400
            15  C8x C    25.7600  -14.8400
            16  C8x C    24.5700  -15.5400
            17  C8x C    28.2800  -17.3600
            18  C8x C    29.1200  -16.2400
            19  N5x N    28.2800  -15.1200
BOND        21
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     2   7 2
            8     4   8 1
            9     1   9 1
            10    9  10 3
            11    5  11 1
            12   11  12 2
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 2
            17   11  16 1
            18   13  17 1
            19   17  18 2
            20   18  19 1
            21   14  19 2

» Japanese version   » Back

DBGET integrated database retrieval system