KEGG   DRUG: D08305Help
Entry
D08305                      Drug                                   

Name
Orphenadrine (INN);
Mialgin (TN)
Formula
C18H23NO
Exact mass
269.178
Mol weight
269.3813
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian, central anticholinergic
Remark
Same as: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
USP drug classification [BR:br08302]
 Skeletal Muscle Relaxants
  Orphenadrine
   D08305  Orphenadrine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Orphenadrine
      D08305  Orphenadrine (INN)
BRITE hierarchy
Other DBs
CAS: 
83-98-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C1a C    19.3200  -19.3200
            2   N1c N    20.5100  -18.6200
            3   C1b C    21.7700  -19.3200
            4   C1b C    22.9600  -18.6200
            5   O2a O    24.1500  -19.3200
            6   C1c C    25.4100  -18.6200
            7   C8y C    26.6000  -19.3200
            8   C8y C    25.4100  -17.2200
            9   C8x C    26.6000  -16.5200
            10  C8x C    26.6000  -15.1200
            11  C8x C    25.3400  -14.4200
            12  C8x C    24.1500  -15.1200
            13  C8y C    24.1500  -16.5200
            14  C8x C    26.6000  -20.7200
            15  C8x C    27.7900  -21.4200
            16  C8x C    29.0500  -20.7200
            17  C8x C    29.0500  -19.3200
            18  C8x C    27.7900  -18.6200
            19  C1a C    22.9600  -17.2200
            20  C1a C    20.5100  -17.2200
BOND        21
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     6   8 1
            8     8   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13    8  13 1
            14    7  14 1
            15   14  15 2
            16   15  16 1
            17   16  17 2
            18   17  18 1
            19    7  18 2
            20   13  19 1
            21    2  20 1

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