KEGG   DRUG: Oxedrine hydrochlorideHelp
Entry
D08309                      Drug                                   

Name
Oxedrine hydrochloride;
Ocuton (TN)
Formula
C9H13NO2. HCl
Exact mass
203.0713
Mol weight
203.666
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01702  Phenethylamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
Remark
ATC code: 
Chemical group: 
Activity
Antihypotensive, Sympathomimetic, alpha-Adrenergic receptor agonist
Comment
Phenethylamine derivative
Target
ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137];
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Salivary secretion
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA08 Oxedrine
      D08309  Oxedrine hydrochloride
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01G DECONGESTANTS AND ANTIALLERGICS
    S01GA Sympathomimetics used as decongestants
     S01GA06 Oxedrine
      D08309  Oxedrine hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Oxedrine
      D08309  Oxedrine hydrochloride
    alpha2-adrenergic receptor
     Oxedrine
      D08309  Oxedrine hydrochloride
BRITE hierarchy
Other DBs
CAS: 
5985-28-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        13
            1   C8x C    21.1400  -17.9200
            2   C8y C    21.1400  -19.3200
            3   C8x C    22.3300  -20.0200
            4   C8x C    23.5200  -19.3200
            5   C8y C    23.5200  -17.9200
            6   C8x C    22.3300  -17.2200
            7   O1a O    19.9500  -20.0200
            8   C1c C    24.7800  -17.2200
            9   C1b C    25.9700  -17.9200
            10  N1b N    27.2300  -17.2200
            11  C1a C    28.4200  -17.9200
            12  O1a O    24.7800  -15.8200
            13  X   Cl   32.5500  -17.9900
BOND        12
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     5   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12    8  12 1

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