KEGG   DRUG: OxiconazoleHelp
Entry
D08313                      Drug                                   

Name
Oxiconazole (INN)
Formula
C18H13Cl4N3O
Exact mass
426.9813
Mol weight
429.1273
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antifungal
 DG01883  Imidazole antifungal
Cyp inhibitor
 DG01643  CYP2C9 inhibitor
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Antifungal
Target
sterol 14alpha-demethylase [KO:K05917]
  Pathway
Steroid biosynthesis
Interaction
CYP inhibition: CYP2C9 [HSA:1559]
Drug interaction
Structure map
Antifungal agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AC Imidazole and triazole derivatives
     D01AC11 Oxiconazole
      D08313  Oxiconazole (INN)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AF Imidazole derivatives
     G01AF17 Oxiconazole
      D08313  Oxiconazole (INN)
USP drug classification [BR:br08302]
 Antifungals
  Oxiconazole
   D08313  Oxiconazole (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 First-class OTC drugs
  Inorganic and organic chemicals
   Oxiconazole
    D08313  Oxiconazole (INN)
 Second-class OTC drugs
  Inorganic and organic chemicals
   Oxiconazole
    D08313  Oxiconazole (INN)
Antiinfectives [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   sterol 14alpha-demethylase inhibitor
    Imidazoles
     Oxiconazole
      D08313  Oxiconazole (INN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP2C9
   Oxiconazole
    D08313  Oxiconazole (INN)
BRITE hierarchy
Other DBs
CAS: 
64211-45-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C2c C    25.3400  -17.9200
            2   C8y C    26.6000  -17.2900
            3   C1b C    24.1500  -17.2200
            4   N2b N    25.3400  -19.3200
            5   C8y C    27.7900  -17.9900
            6   C8x C    26.6000  -15.8900
            7   N4y N    24.1500  -15.8200
            8   O2a O    24.1500  -20.0200
            9   C8x C    29.0500  -17.2900
            10  X   Cl   27.7900  -19.3900
            11  C8x C    27.8600  -15.1900
            12  C8x C    25.2700  -15.0500
            13  C8x C    23.0300  -15.0500
            14  C1b C    22.9600  -19.3200
            15  C8y C    29.0500  -15.8900
            16  C8x C    24.8500  -13.7200
            17  N5x N    23.4500  -13.7200
            18  C8y C    21.7000  -20.0200
            19  X   Cl   30.3100  -15.2600
            20  C8y C    20.5100  -19.3200
            21  C8x C    21.7000  -21.4200
            22  C8x C    19.3200  -20.0200
            23  X   Cl   20.5100  -17.9200
            24  C8x C    20.5100  -22.1200
            25  C8y C    19.3200  -21.4200
            26  X   Cl   18.0600  -22.1200
BOND        28
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     2   6 2
            6     3   7 1
            7     4   8 1
            8     5   9 2
            9     5  10 1
            10    6  11 1
            11    7  12 1
            12    7  13 1
            13    8  14 1
            14    9  15 1
            15   12  16 2
            16   13  17 2
            17   14  18 1
            18   15  19 1
            19   18  20 1
            20   18  21 2
            21   20  22 2
            22   20  23 1
            23   21  24 1
            24   22  25 1
            25   25  26 1
            26   11  15 2
            27   16  17 1
            28   24  25 2

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