KEGG   DRUG: D08325Help
Entry
D08325                      Drug                                   

Name
Oxyphencyclimine (INN)
Formula
C20H28N2O3
Exact mass
344.21
Mol weight
344.4479
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antispasmodic;
Gastric secretory inhibitor;
Parasympatholytic
Remark
Same as: 
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor M3 antagonist [HSA:1131] [KO:K04131]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03A DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
    A03AA Synthetic anticholinergics, esters with tertiary amino group
     A03AA01 Oxyphencyclimine
      D08325  Oxyphencyclimine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Oxyphencyclimine
    D08325  Oxyphencyclimine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor M3
     Oxyphencyclimine
      D08325  Oxyphencyclimine (INN)
BRITE hierarchy
Other DBs
CAS: 
125-53-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1x C    18.6900  -17.2200
            2   C1x C    18.6900  -18.6200
            3   N1y N    19.8800  -19.3200
            4   C2y C    21.1400  -18.6200
            5   N2x N    21.1400  -17.2200
            6   C1x C    19.8800  -16.5200
            7   C1b C    22.3300  -19.3200
            8   O7a O    23.5900  -18.6200
            9   C7a C    24.7800  -19.3200
            10  C1d C    25.9700  -18.6200
            11  C8y C    27.2300  -19.3200
            12  C1y C    25.9700  -17.2200
            13  C1x C    27.1600  -16.5200
            14  C1x C    27.1600  -15.1200
            15  C1x C    25.9700  -14.4200
            16  C1x C    24.7800  -15.1200
            17  C1x C    24.7800  -16.5200
            18  C8x C    27.2300  -20.7200
            19  C8x C    28.4200  -21.4200
            20  C8x C    29.6100  -20.7200
            21  C8x C    29.6100  -19.3200
            22  C8x C    28.4200  -18.6200
            23  O1a O    27.2300  -17.9200
            24  O6a O    24.7800  -20.7200
            25  C1a C    19.8800  -20.7200
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   10  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   12  17 1
            19   11  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   11  22 1
            25   10  23 1
            26    9  24 2
            27    3  25 1

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