KEGG   DRUG: D08355Help
Entry
D08355                      Drug                                   

Name
Pheniramine (INN)
Formula
C16H20N2
Exact mass
240.1626
Mol weight
240.3434
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AB Substituted alkylamines
     R06AB05 Pheniramine
      D08355  Pheniramine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Category 2
  Inorganic and organic chemicals
   Pheniramine
    D08355  Pheniramine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Pheniramine
      D08355  Pheniramine (INN)
BRITE hierarchy
Other DBs
CAS: 
86-21-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8x C    27.8600  -19.3900
            2   C8x C    27.8600  -20.7900
            3   C8x C    26.6700  -21.4900
            4   C8x C    25.4100  -20.7900
            5   C8y C    25.4100  -19.3900
            6   N5x N    26.6700  -18.6900
            7   C1c C    24.2200  -18.6900
            8   C8y C    22.9600  -19.3900
            9   C1b C    24.2200  -17.2900
            10  C8x C    22.9600  -20.7900
            11  C8x C    21.7700  -21.4900
            12  C8x C    20.5100  -20.7900
            13  C8x C    20.5100  -19.3900
            14  C8x C    21.7700  -18.6900
            15  C1b C    25.4100  -16.5900
            16  N1c N    25.4100  -15.1200
            17  C1a C    26.6700  -14.4200
            18  C1a C    24.2200  -14.4200
BOND        19
            1    10  11 1
            2    11  12 2
            3    12  13 1
            4    13  14 2
            5    14   8 1
            6     9  15 1
            7     5   7 1
            8    15  16 1
            9    16  17 1
            10    7   8 1
            11   16  18 1
            12    1   2 2
            13    7   9 1
            14    2   3 1
            15    3   4 2
            16    4   5 1
            17    5   6 2
            18    6   1 1
            19    8  10 2

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