KEGG   DRUG: PirbuterolHelp
Entry
D08387                      Drug                                   

Name
Pirbuterol (INN)
Formula
C12H20N2O3
Exact mass
240.1474
Mol weight
240.2988
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01456  Adrenergic receptor agonist
  DG01455  beta-Adrenergic receptor agonist
   DG01452  beta2-Adrenergic receptor agonist
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
Remark
Same as: 
ATC code: 
Chemical group: 
Activity
Bronchodilator, beta2-Adrenergic receptor agonist
Comment
Phenethylamine derivative
Target
ADRB2 [HSA:154] [KO:K04142]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AC Selective beta-2-adrenoreceptor agonists
     R03AC08 Pirbuterol
      D08387  Pirbuterol (INN)
   R03C ADRENERGICS FOR SYSTEMIC USE
    R03CC Selective beta-2-adrenoreceptor agonists
     R03CC07 Pirbuterol
      D08387  Pirbuterol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Pirbuterol
      D08387  Pirbuterol (INN)
BRITE hierarchy
Other DBs
CAS: 
38677-81-5
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        17
            1   C8y C    18.1300  -16.1700
            2   N5x N    16.8700  -16.8700
            3   C1c C    19.3200  -16.8700
            4   C8x C    18.1300  -14.7700
            5   C8y C    15.6800  -16.1700
            6   C1b C    20.5100  -16.1700
            7   O1a O    19.3200  -18.2700
            8   C8x C    16.8700  -14.0700
            9   C8y C    15.6800  -14.7700
            10  C1b C    14.4900  -16.8700
            11  N1b N    21.7000  -16.8700
            12  O1a O    14.4900  -14.0700
            13  O1a O    13.1600  -16.1700
            14  C1d C    22.9600  -16.1700
            15  C1a C    24.1500  -15.4700
            16  C1a C    23.6600  -17.3600
            17  C1a C    22.2600  -14.9800
BOND        17
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 2
            5     3   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     5  10 1
            10    6  11 1
            11    9  12 1
            12   10  13 1
            13   11  14 1
            14    8   9 2
            15   14  15 1
            16   14  16 1
            17   14  17 1

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