KEGG   DRUG: D08392Help
Entry
D08392                      Drug                                   

Name
Pirlindole (INN);
Pyrazidol (TN)
Formula
C15H18N2
Exact mass
226.147
Mol weight
226.3168
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Target
reversible monoamine oxidase A (MAO-A) inhibitor [HSA:4128] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase A (MAO-A) [HSA:4128] [KO:K00274]
    Pirlindole
     D08392  Pirlindole (INN)
BRITE hierarchy
Other DBs
CAS: 
60762-57-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        17
            1   C8y C    24.8500  -20.3700
            2   C8x C    24.8500  -21.7700
            3   C8x C    26.0400  -22.4700
            4   C8y C    27.2300  -21.7700
            5   C8y C    27.2300  -20.3700
            6   C8x C    26.0400  -19.6700
            7   N4y N    28.5600  -22.1900
            8   C8y C    29.4000  -21.0700
            9   C8y C    28.5600  -19.9500
            10  C1y C    30.8000  -21.0700
            11  C1a C    23.6600  -19.6700
            12  C1x C    29.3300  -18.6200
            13  C1x C    31.5000  -19.8100
            14  C1x C    30.7300  -18.6200
            15  C1x C    29.3300  -23.4500
            16  C1x C    30.7300  -23.4500
            17  N1x N    31.4300  -22.2600
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    5   9 1
            11    8  10 1
            12    1  11 1
            13   12   9 1
            14   10  13 1
            15   13  14 1
            16   12  14 1
            17    7  15 1
            18   15  16 1
            19   16  17 1
            20   17  10 1

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