KEGG   DRUG: D08395Help
Entry
D08395                      Drug                                   

Name
Piroheptine (INN)
Formula
C22H25N
Exact mass
303.1987
Mol weight
303.4406
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Piroheptine
      D08395  Piroheptine (INN)
BRITE hierarchy
Other DBs
CAS: 
16378-21-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        23
            1   C1x C    23.4500  -21.8400
            2   C8y C    22.6100  -20.7200
            3   C8y C    22.8900  -19.3900
            4   C2y C    24.1500  -18.8300
            5   C1x C    24.8500  -21.8400
            6   C8y C    25.4100  -19.3900
            7   C8y C    25.6900  -20.7900
            8   C8x C    21.9100  -18.4100
            9   C8x C    20.5800  -18.7600
            10  C8x C    20.2300  -20.1600
            11  C8x C    21.2100  -21.1400
            12  C8x C    27.0200  -21.2100
            13  C8x C    28.0700  -20.3000
            14  C8x C    27.7900  -18.9000
            15  C8x C    26.4600  -18.4800
            16  C2y C    24.1500  -17.4300
            17  C1y C    25.2700  -16.5200
            18  N1y N    24.7800  -15.1900
            19  C1x C    23.3100  -15.2600
            20  C1x C    22.9600  -16.6600
            21  C1a C    26.6000  -16.9400
            22  C1b C    25.4100  -14.0000
            23  C1a C    26.8100  -14.0000
BOND        26
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    4  16 2
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   16  20 1
            24   17  21 1
            25   18  22 1
            26   22  23 1

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