KEGG   DRUG: D08411Help
Entry
D08411                      Drug                                   

Name
Prazosin (INN);
Minipress (TN)
Formula
C19H21N5O4
Exact mass
383.1594
Mol weight
383.4011
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive;
Vasodilator, peripheric
Remark
Same as: 
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Transporter inhibition: SLC22A3 [HSA:6581]
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
    C02CA Alpha-adrenoreceptor antagonists
     C02CA01 Prazosin
      D08411  Prazosin (INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Alpha-adrenergic Blocking Agents
   Prazosin
    D08411  Prazosin (INN)
 Genitourinary Agents
  Benign Prostatic Hypertrophy Agents
   Prazosin
    D08411  Prazosin (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Prazosin
      D08411  Prazosin (INN)
BRITE hierarchy
Other DBs
CAS: 
19216-56-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C8y C    27.1600  -19.6700
            2   C8y C    27.1600  -18.2700
            3   C8x C    28.3500  -20.3700
            4   C8y C    25.9000  -20.3700
            5   N5x N    25.9000  -17.5700
            6   C8x C    28.3500  -17.5700
            7   C8y C    29.5400  -19.6700
            8   N5x N    24.7100  -19.6700
            9   N1a N    25.9000  -21.7700
            10  C8y C    24.7100  -18.2700
            11  C8y C    29.5400  -18.2700
            12  O2a O    30.8000  -20.3700
            13  N1y N    23.5200  -17.5700
            14  O2a O    30.8000  -17.5700
            15  C1a C    31.9900  -19.6700
            16  C1x C    23.5200  -16.2400
            17  C1x C    22.2600  -18.2700
            18  C1a C    31.9900  -18.2700
            19  C1x C    22.2600  -15.4700
            20  C1x C    21.0700  -17.5700
            21  N1y N    21.0700  -16.2400
            22  C5a C    19.8800  -15.4700
            23  C8y C    18.6200  -16.2400
            24  O5a O    19.8800  -14.0700
            25  C8x C    18.2700  -17.5700
            26  O2x O    17.5000  -15.4000
            27  C8x C    16.8700  -17.5700
            28  C8x C    16.3800  -16.3100
BOND        31
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 2
            8     4   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1
            12   10  13 1
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   13  17 1
            17   14  18 1
            18   16  19 1
            19   17  20 1
            20   19  21 1
            21   21  22 1
            22   22  23 1
            23   22  24 2
            24   23  25 2
            25   23  26 1
            26   25  27 1
            27   26  28 1
            28    7  11 1
            29    8  10 1
            30   20  21 1
            31   27  28 2

» Japanese version   » Back

DBGET integrated database retrieval system