| Entry |
|
|---|
| Name |
Prazosin (INN);
Minipress (TN)
|
|---|
| Formula |
C19H21N5O4
|
|---|
| Exact mass |
383.1594
|
|---|
| Mol weight |
383.4011
|
|---|
| Structure |
     |
|---|
| Activity |
Antihypertensive;
Vasodilator, peripheric
|
|---|
| Remark |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
Transporter inhibition: SLC22A3 [HSA: 6581]
 |
|---|
| Pathway map |
|
|---|
| Structure map |
| alpha-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
C02CA Alpha-adrenoreceptor antagonists
C02CA01 Prazosin
D08411 Prazosin (INN)
USP drug classification [BR:br08302]
Cardiovascular Agents
Alpha-adrenergic Blocking Agents
Prazosin
D08411 Prazosin (INN)
Genitourinary Agents
Benign Prostatic Hypertrophy Agents
Alpha-1 Adrenergic Blocking Agents
Prazosin
D08411 Prazosin (INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
alpha1-adrenergic receptor [HSA:146 147 148] [KO:K04137 K04136 K04135]
Prazosin [ATC:C02CA01]
D08411 Prazosin (INN)
 |
|---|
| Other DBs |
CAS: 19216-56-9 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 28
1 C8y C 27.1600 -19.6700
2 C8y C 27.1600 -18.2700
3 C8x C 28.3500 -20.3700
4 C8y C 25.9000 -20.3700
5 N5x N 25.9000 -17.5700
6 C8x C 28.3500 -17.5700
7 C8y C 29.5400 -19.6700
8 N5x N 24.7100 -19.6700
9 N1a N 25.9000 -21.7700
10 C8y C 24.7100 -18.2700
11 C8y C 29.5400 -18.2700
12 O2a O 30.8000 -20.3700
13 N1y N 23.5200 -17.5700
14 O2a O 30.8000 -17.5700
15 C1a C 31.9900 -19.6700
16 C1x C 23.5200 -16.2400
17 C1x C 22.2600 -18.2700
18 C1a C 31.9900 -18.2700
19 C1x C 22.2600 -15.4700
20 C1x C 21.0700 -17.5700
21 N1y N 21.0700 -16.2400
22 C5a C 19.8800 -15.4700
23 C8y C 18.6200 -16.2400
24 O5a O 19.8800 -14.0700
25 C8x C 18.2700 -17.5700
26 O2x O 17.5000 -15.4000
27 C8x C 16.8700 -17.5700
28 C8x C 16.3800 -16.3100
BOND 31
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 4 9 1
9 5 10 2
10 6 11 2
11 7 12 1
12 10 13 1
13 11 14 1
14 12 15 1
15 13 16 1
16 13 17 1
17 14 18 1
18 16 19 1
19 17 20 1
20 19 21 1
21 21 22 1
22 22 23 1
23 22 24 2
24 23 25 2
25 23 26 1
26 25 27 1
27 26 28 1
28 7 11 1
29 8 10 1
30 20 21 1
31 27 28 2
|
|---|
