KEGG   DRUG: D08425Help
Entry
D08425                      Drug                                   

Name
Procyclidine (INN)
Formula
C19H29NO
Exact mass
287.2249
Mol weight
287.4397
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian, central anticholinergic
Remark
Same as: 
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA04 Procyclidine
      D08425  Procyclidine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Procyclidine
      D08425  Procyclidine (INN)
BRITE hierarchy
Other DBs
CAS: 
77-37-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   N1y N    21.6300  -19.3200
            2   C1b C    22.8200  -18.6200
            3   C1b C    24.0800  -19.3200
            4   C1d C    25.2700  -18.6200
            5   C8y C    26.4600  -19.3200
            6   C8x C    27.7200  -18.6200
            7   C8x C    28.9100  -19.3200
            8   C1x C    20.4400  -18.6200
            9   C1x C    19.3900  -19.5300
            10  C1x C    19.9500  -20.8600
            11  C1x C    21.3500  -20.7200
            12  C1y C    25.2700  -17.2200
            13  C1x C    26.4600  -16.5200
            14  C1x C    26.4600  -15.1200
            15  C1x C    25.2700  -14.4200
            16  C1x C    24.0800  -15.1200
            17  C1x C    24.0800  -16.5200
            18  C8x C    26.4600  -20.7200
            19  C8x C    27.7200  -21.4200
            20  C8x C    28.9100  -20.7200
            21  O1a O    26.4600  -17.9200
BOND        23
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 2
            7     1   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11    1  11 1
            12    4  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   12  17 1
            19    5  18 2
            20   18  19 1
            21   19  20 2
            22   20   7 1
            23    4  21 1

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