KEGG   DRUG: D08426Help
Entry
D08426                      Drug                                   

Name
Profenamine (INN)
Formula
C19H24N2S
Exact mass
312.166
Mol weight
312.4723
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiparkinsonian, central anticholinergic
Remark
ATC code: 
Drug group: 
Comment
centrally active anticholinergic drugs
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Phenothiazines
Antiparkinsonian agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA05 Profenamine
      D08426  Profenamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Profenamine
      D08426  Profenamine (INN)
BRITE hierarchy
Other DBs
CAS: 
522-00-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8x C    20.5100  -19.3200
            2   C8x C    20.5100  -20.7200
            3   C8x C    21.7700  -21.4200
            4   C8y C    22.9600  -20.7200
            5   C8y C    22.9600  -19.3200
            6   C8x C    21.7700  -18.6200
            7   S2x S    24.1500  -21.4200
            8   C8y C    25.4100  -20.7200
            9   C8y C    25.4100  -19.3200
            10  N4y N    24.1500  -18.6200
            11  C8x C    26.6000  -21.4200
            12  C8x C    27.7900  -20.7200
            13  C8x C    27.7900  -19.3200
            14  C8x C    26.6000  -18.6200
            15  C1b C    24.1500  -17.2200
            16  C1c C    25.4100  -16.5200
            17  C1a C    26.6000  -17.2200
            18  N1c N    25.4100  -15.1200
            19  C1b C    26.6000  -14.4200
            20  C1b C    24.1500  -14.4200
            21  C1a C    22.9600  -15.1200
            22  C1a C    27.7900  -15.1200
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   16  18 1
            21   18  19 1
            22   18  20 1
            23   20  21 1
            24   19  22 1

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