KEGG   DRUG: ProfenamineHelp
Entry
D08426                      Drug                                   

Name
Profenamine (INN)
Formula
C19H24N2S
Exact mass
312.166
Mol weight
312.4723
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
 DG01745  Anticholinergic antiparkinson agent
Unclassified
  DG01745  Anticholinergic antiparkinson agent
Remark
ATC code: 
Chemical group: 
Activity
Antiparkinsonian, Muscarinic acetylcholine receptor antagonist
Comment
Phenothiazine derivative
centrally active anticholinergic drugs
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Structure map
Phenothiazines
Antiparkinsonian agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04A ANTICHOLINERGIC AGENTS
    N04AA Tertiary amines
     N04AA05 Profenamine
      D08426  Profenamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Profenamine
      D08426  Profenamine (INN)
BRITE hierarchy
Other DBs
CAS: 
522-00-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8x C    20.5100  -19.3200
            2   C8x C    20.5100  -20.7200
            3   C8x C    21.7700  -21.4200
            4   C8y C    22.9600  -20.7200
            5   C8y C    22.9600  -19.3200
            6   C8x C    21.7700  -18.6200
            7   S2x S    24.1500  -21.4200
            8   C8y C    25.4100  -20.7200
            9   C8y C    25.4100  -19.3200
            10  N4y N    24.1500  -18.6200
            11  C8x C    26.6000  -21.4200
            12  C8x C    27.7900  -20.7200
            13  C8x C    27.7900  -19.3200
            14  C8x C    26.6000  -18.6200
            15  C1b C    24.1500  -17.2200
            16  C1c C    25.4100  -16.5200
            17  C1a C    26.6000  -17.2200
            18  N1c N    25.4100  -15.1200
            19  C1b C    26.6000  -14.4200
            20  C1b C    24.1500  -14.4200
            21  C1a C    22.9600  -15.1200
            22  C1a C    27.7900  -15.1200
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    8  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 2
            16    9  14 1
            17   10  15 1
            18   15  16 1
            19   16  17 1
            20   16  18 1
            21   18  19 1
            22   18  20 1
            23   20  21 1
            24   19  22 1

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