KEGG   DRUG: D08453Help
Entry
D08453                      Drug                                   

Name
Pargyline (INN)
Formula
C11H13N
Exact mass
159.1048
Mol weight
159.2276
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Same as: 
ATC code: 
Drug group: 
Target
monoamine oxidase (MAO) inhibitor [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02K OTHER ANTIHYPERTENSIVES
    C02KC MAO inhibitors
     C02KC01 Pargyline
      D08453  Pargyline (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase (MAO)
    Pargyline
     D08453  Pargyline (INN)
BRITE hierarchy
Other DBs
CAS: 
555-57-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        12
            1   C8y C    24.5000  -17.6400
            2   C1b C    25.6900  -16.9400
            3   C8x C    24.5000  -19.0400
            4   C8x C    23.3100  -16.9400
            5   N1c N    26.9500  -17.6400
            6   C8x C    23.3100  -19.7400
            7   C8x C    22.1200  -17.6400
            8   C1b C    28.1400  -16.9400
            9   C1a C    26.9500  -19.0400
            10  C8x C    22.1200  -19.0400
            11  C3b C    29.3300  -17.6400
            12  C3a C    30.5900  -18.3400
BOND        12
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 1
            8     5   9 1
            9     6  10 1
            10    8  11 1
            11   11  12 3
            12    7  10 2

» Japanese version   » Back

DBGET integrated database retrieval system