KEGG   DRUG: D08466Help
Entry
D08466                      Drug                                   

Name
Ramosetron (INN)
Formula
C17H17N3O
Exact mass
279.1372
Mol weight
279.3364
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Serotonin antagonist
Target
5-HT3-receptor antagonist [HSA:3359 9177 170572 200909 285242] [KO:K04819]
  Pathway
hsa04726  Serotonergic synapse  
 
Metabolism
Enzyme: CYP1A1 [HSA:1543], CYP1A2 [HSA:1544], CYP2D6 [HSA:1565]
Interaction
Drug interaction
Structure map
Serotonin receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT3-receptor
     Ramosetron
      D08466  Ramosetron (INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP1A1
   Ramosetron
    D08466  Ramosetron (INN)
  CYP1A2
   Ramosetron
    D08466  Ramosetron (INN)
  CYP2D6
   Ramosetron
    D08466  Ramosetron (INN)
BRITE hierarchy
Other DBs
CAS: 
132036-88-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        21
            1   C1x C    23.1700  -17.0100
            2   C1y C    23.1700  -18.4100
            3   C5a C    24.3600  -19.1100
            4   C8y C    25.6200  -18.4100
            5   C8x C    25.6200  -17.0100
            6   C1x C    21.9800  -16.3100
            7   C8y C    20.7200  -17.0100
            8   C8y C    20.7200  -18.4100
            9   C1x C    21.9800  -19.1100
            10  C8y C    26.9500  -18.8300
            11  C8y C    27.7200  -17.7100
            12  N4y N    26.9500  -16.5900
            13  C8x C    27.5100  -20.0900
            14  C8x C    28.9100  -20.3000
            15  C8x C    29.6800  -19.1100
            16  C8x C    29.1200  -17.8500
            17  O5a O    24.3600  -20.5100
            18  N5x N    19.3900  -16.5900
            19  C8x C    18.6200  -17.7100
            20  N4x N    19.3900  -18.8300
            21  C1a C    27.6500  -15.3300
BOND        24
            1     1   2 1
            2     2   3 1 #Up
            3     3   4 1
            4     4   5 2
            5     1   6 1
            6     6   7 1
            7     7   8 2
            8     8   9 1
            9     2   9 1
            10    4  10 1
            11   10  11 2
            12   11  12 1
            13    5  12 1
            14   10  13 1
            15   13  14 2
            16   14  15 1
            17   15  16 2
            18   11  16 1
            19    3  17 2
            20    7  18 1
            21   18  19 2
            22   19  20 1
            23    8  20 1
            24   12  21 1

» Japanese version   » Back

DBGET integrated database retrieval system