KEGG   DRUG: D08469Help
Entry
D08469                      Drug                                   

Name
Rasagiline (USAN/INN);
Azilect (TN)
Formula
C12H13N
Exact mass
171.1048
Mol weight
171.2383
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of Parkinson's disease;
Neuroprotective;
Enzyme inhibitor, monoaminoxydase type B
Remark
ATC code: 
Drug group: 
Target
monoamine oxidase B (MAO-B) inhibitor [HSA:4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Structure map
Antidepressants
Antiparkinsonian agents
Catecholamine transferase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04B DOPAMINERGIC AGENTS
    N04BD Monoamine oxidase B inhibitors
     N04BD02 Rasagiline
      D08469  Rasagiline (USAN/INN)
USP drug classification [BR:br08302]
 Antiparkinson Agents
  Monoamine Oxidase B (MAO-B) Inhibitors
   Rasagiline
    D08469  Rasagiline (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase B (MAO-B)
    Rasagiline
     D08469  Rasagiline (INN)
BRITE hierarchy
Other DBs
CAS: 
136236-51-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        13
            1   C8y C    22.8900  -17.7100
            2   C8y C    22.8900  -16.3100
            3   C8x C    21.7000  -15.6100
            4   C8x C    20.5100  -16.3100
            5   C8x C    20.5100  -17.7100
            6   C8x C    21.7000  -18.4100
            7   C1y C    24.2200  -18.1300
            8   C1x C    25.0600  -17.0100
            9   C1x C    24.2200  -15.8200
            10  N1b N    24.2200  -19.5300
            11  C1b C    25.4800  -20.2300
            12  C3b C    26.6700  -19.5300
            13  C3a C    27.8600  -18.8300
BOND        14
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     8   9 1
            10    2   9 1
            11    7  10 1 #Up
            12   10  11 1
            13   11  12 1
            14   12  13 3

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