KEGG   DRUG: RimantadineHelp
Entry
D08483                      Drug                                   

Name
Rimantadine (INN)
Formula
C12H21N
Exact mass
179.1674
Mol weight
179.3018
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antiviral
 DG02841  Viral uncoating inhibitor
Remark
Same as: C07236
ATC code: J05AC02
Chemical structure group: DG00650
Product (DG00650): D00901<US>
Efficacy
Antiviral, M2 protein inhibitor
Comment
Adamantane derivative
Target
Influenza A virus M2 proton channel [KO:K19394]
  Pathway
ko05164  Influenza A
Structure map
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AC Cyclic amines
     J05AC02 Rimantadine
      D08483  Rimantadine (INN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-influenza Agents
   Rimantadine
    D08483  Rimantadine (INN)
BRITE hierarchy
Other DBs
CAS: 13392-28-4
PubChem: 96025169
ChEBI: 49886
ChEMBL: CHEMBL1201272 CHEMBL959
DrugBank: DB00478
LigandBox: D08483
NIKKAJI: J8.105A
KCF data Show

ATOM        13
            1   C1z C    24.7800  -17.0100
            2   C1c C    24.7800  -15.8200
            3   C1x C    24.1500  -18.5500
            4   C1x C    23.7300  -17.6400
            5   C1x C    25.9000  -17.6400
            6   C1a C    23.7300  -15.1900
            7   N1a N    25.9000  -15.1900
            8   C1y C    24.1500  -19.6700
            9   C1y C    23.7300  -18.9000
            10  C1y C    25.9000  -18.9000
            11  C1x C    22.4700  -20.1600
            12  C1x C    25.3400  -20.7200
            13  C1x C    24.7800  -19.4600
BOND        15
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 1
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    8  11 1
            11    8  12 1
            12    9  13 1
            13    9  11 1
            14   10  12 1
            15   10  13 1

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