KEGG   DRUG: D08507Help
Entry
D08507                      Drug                                   

Name
Sarmazenil (INN);
Sarmazol [veterinary] (TN)
Formula
C15H14ClN3O3
Exact mass
319.0724
Mol weight
319.743
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidote, benzodiazepines
Target
GABAA-receptor (benzodiazepine binding site) inverse agonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site)
     Sarmazenil
      D08507  Sarmazenil (INN)
BRITE hierarchy
Other DBs
CAS: 
78771-13-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8y C    36.4666  -20.1095
            2   N4y N    37.7334  -19.5231
            3   C8y C    38.9897  -20.1421
            4   C1x C    39.2852  -21.5005
            5   C8y C    36.1405  -21.4802
            6   N1y N    38.4072  -22.5943
            7   C5x C    37.0058  -22.5812
            8   C8x C    35.4491  -19.1479
            9   C8x C    34.1076  -19.5482
            10  C8x C    33.7815  -20.9189
            11  C8y C    34.7990  -21.8806
            12  X   Cl   34.4679  -23.2724
            13  O5x O    36.3812  -23.8506
            14  C8y C    39.9667  -19.1386
            15  N5x N    39.3142  -17.8993
            16  C8x C    37.9339  -18.1369
            17  C7a C    41.3698  -19.0845
            18  O7a O    42.1277  -20.2873
            19  O6a O    42.0121  -17.8659
            20  C1b C    43.5400  -20.2908
            21  C1a C    44.2409  -21.5119
            22  C1a C    39.0167  -23.8811
BOND        24
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     1   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    5  11 2
            13   11  12 1
            14    7  13 2
            15    3  14 2
            16   14  15 1
            17   15  16 2
            18    2  16 1
            19   14  17 1
            20   17  18 1
            21   17  19 2
            22   18  20 1
            23   20  21 1
            24    6  22 1

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