KEGG   DRUG: D08508Help
Entry
D08508                      Drug                                   

Name
Sarpogrelate (INN)
Formula
C24H31NO6
Exact mass
429.2151
Mol weight
429.506
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anticoagulant, platelet aggregation inhibitor
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Metabolism
Enzyme: CYP1A2 [HSA:1544], CYP2C9 [HSA:1559], CYP2C19 [HSA:1557], CYP2D6 [HSA:1565], CYP3A4 [HSA:1576]
Interaction
Drug interaction
Structure map
Antithrombosis agents
Serotonin receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2A-receptor
     Sarpogrelate
      D08508  Sarpogrelate (INN)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP1A2
   Sarpogrelate
    D08508  Sarpogrelate (INN)
  CYP2C9
   Sarpogrelate
    D08508  Sarpogrelate (INN)
  CYP2C19
   Sarpogrelate
    D08508  Sarpogrelate (INN)
  CYP2D6
   Sarpogrelate
    D08508  Sarpogrelate (INN)
  CYP3A4
   Sarpogrelate
    D08508  Sarpogrelate (INN)
BRITE hierarchy
Other DBs
CAS: 
125926-17-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        31
            1   C8y C    19.9500  -17.9900
            2   O2a O    21.1400  -17.2900
            3   C8x C    18.7600  -17.2900
            4   C8y C    19.9500  -19.3900
            5   C1b C    22.3300  -17.9900
            6   C8x C    17.5000  -17.9900
            7   C8x C    18.7600  -20.0900
            8   C1c C    23.5900  -17.2900
            9   C8x C    17.5000  -19.3900
            10  O7a O    24.7800  -17.9900
            11  C1b C    23.5900  -15.8900
            12  C7a C    25.9700  -17.2900
            13  C1b C    27.2300  -17.9900
            14  C1b C    28.4200  -17.2900
            15  C6a C    29.6100  -17.9900
            16  O6a O    30.8700  -17.2900
            17  O6a O    25.9700  -15.8900
            18  O6a O    29.6100  -19.3900
            19  C1b C    21.1400  -20.0900
            20  C1b C    22.3300  -19.3900
            21  C8y C    23.5900  -20.0200
            22  C8x C    23.5900  -21.4200
            23  C8x C    24.7800  -22.1200
            24  C8x C    25.9700  -21.4200
            25  C8y C    25.9700  -20.0200
            26  C8x C    24.7800  -19.3200
            27  O2a O    27.2300  -19.3200
            28  C1a C    28.4200  -20.0200
            29  N1c N    22.3300  -15.1900
            30  C1a C    22.3300  -13.7900
            31  C1a C    21.1400  -15.8900
BOND        32
            1    15  16 1
            2     7   9 1
            3    12  17 2
            4    15  18 2
            5     1   2 1
            6     4  19 1
            7     1   3 2
            8    19  20 1
            9     1   4 1
            10   20  21 1
            11    2   5 1
            12    3   6 1
            13    4   7 2
            14    5   8 1
            15    6   9 2
            16   21  22 2
            17   22  23 1
            18   23  24 2
            19   24  25 1
            20   25  26 2
            21   26  21 1
            22    8  10 1
            23   25  27 1
            24    8  11 1
            25   27  28 1
            26   10  12 1
            27   11  29 1
            28   12  13 1
            29   29  30 1
            30   13  14 1
            31   29  31 1
            32   14  15 1

» Japanese version   » Back

DBGET integrated database retrieval system