KEGG   DRUG: D08531Help
Entry
D08531                      Drug                                   

Name
Streptomycin (INN);
SM;
Streptomycin (TN)
Formula
C21H39N7O12
Exact mass
581.2657
Mol weight
581.5741
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Streptomyces griseus [TAX:1911]
Activity
Antibiotic;
Aminoglycoside
Remark
Same as: 
ATC code: 
Comment
Natural product
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA04 Streptomycin
      D08531  Streptomycin (INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GA Streptomycins
     J01GA01 Streptomycin
      D08531  Streptomycin (INN)
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Streptomycin
    D08531  Streptomycin (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor [KO:K01977]
    Aminoglycosides
     Streptomycin [ATC:A07AA04 J01GA01]
      D08531  Streptomycin (INN)
BRITE hierarchy
Other DBs
CAS: 
57-92-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        40
            1   C1y C    24.0800  -19.7400
            2   C1y C    24.5000  -18.4800
            3   C1z C    22.7500  -19.7400
            4   O2a O    25.7600  -20.8600
            5   O2a O    26.0400  -17.1500
            6   O2x O    23.3800  -17.7800
            7   C1y C    22.4000  -18.4800
            8   C4a C    21.4900  -20.5100
            9   O1a O    22.7500  -21.0000
            10  C1y C    24.6400  -22.9600
            11  C1y C    25.9700  -15.5400
            12  C1a C    21.1400  -18.1300
            13  O4a O    20.3000  -19.8100
            14  C1y C    24.6400  -24.2900
            15  O2x O    23.5200  -22.2600
            16  C1y C    24.8500  -14.8400
            17  C1y C    27.1600  -14.8400
            18  C1y C    23.5200  -24.9200
            19  C1y C    22.4000  -22.9600
            20  C1y C    24.8500  -13.5100
            21  N1b N    23.0300  -15.6800
            22  C1y C    27.1600  -13.5100
            23  O1a O    28.2800  -15.5400
            24  C1y C    22.4000  -24.2900
            25  O1a O    23.5200  -26.2500
            26  C1b C    21.2800  -22.2600
            27  C1y C    25.9700  -12.8800
            28  O1a O    23.9400  -12.8100
            29  C2c C    21.9100  -15.0500
            30  O1a O    28.2800  -12.8800
            31  O1a O    21.2800  -24.9200
            32  O1a O    20.0900  -22.9600
            33  N1b N    25.9700  -11.5500
            34  N1a N    20.7900  -15.6800
            35  N2a N    21.9100  -13.7200
            36  C2c C    24.8500  -10.9200
            37  N2a N    24.8500   -9.5900
            38  N1a N    23.7300  -11.5500
            39  N1b N    25.9000  -24.9900
            40  C1a C    27.0900  -24.2900
BOND        42
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1 #Up
            5     2   6 1
            6     3   7 1
            7     3   8 1 #Up
            8     3   9 1
            9    10   4 1 #Up
            10   11   5 1 #Down
            11    7  12 1 #Down
            12    8  13 2
            13   10  14 1
            14   10  15 1
            15   11  16 1
            16   11  17 1
            17   14  18 1
            18   15  19 1
            19   16  20 1
            20   16  21 1 #Up
            21   17  22 1
            22   17  23 1 #Up
            23   18  24 1
            24   18  25 1 #Down
            25   19  26 1 #Down
            26   20  27 1
            27   20  28 1 #Down
            28   21  29 1
            29   22  30 1 #Down
            30   24  31 1 #Up
            31   26  32 1
            32   27  33 1 #Up
            33   29  34 1
            34   29  35 2
            35   33  36 1
            36   36  37 2
            37   36  38 1
            38    6   7 1
            39   19  24 1
            40   22  27 1
            41   14  39 1 #Up
            42   39  40 1

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