KEGG   DRUG: D08569Help
Entry
D08569                      Drug                                   

Name
Terazosin (INN);
Terazosabb (TN)
Formula
C19H25N5O4
Exact mass
387.1907
Mol weight
387.4329
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
Same as: 
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor antagonist [HSA:148 147 146] [KO:K04135 K04136 K04137]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
    G04CA Alpha-adrenoreceptor antagonists
     G04CA03 Terazosin
      D08569  Terazosin (INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Alpha-adrenergic Blocking Agents
   Terazosin
    D08569  Terazosin (INN)
 Genitourinary Agents
  Benign Prostatic Hypertrophy Agents
   Terazosin
    D08569  Terazosin (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Terazosin
      D08569  Terazosin (INN)
BRITE hierarchy
Other DBs
CAS: 
63590-64-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C8y C    27.0900  -19.6700
            2   C8y C    27.0900  -18.2700
            3   C8x C    28.2800  -20.3700
            4   C8y C    25.9000  -20.3700
            5   N5x N    25.9000  -17.5700
            6   C8x C    28.2800  -17.5700
            7   C8y C    29.5400  -19.6700
            8   N5x N    24.6400  -19.6700
            9   N1a N    25.9000  -21.7700
            10  C8y C    24.6400  -18.2700
            11  C8y C    29.5400  -18.2700
            12  O2a O    30.7300  -20.3700
            13  N1y N    23.4500  -17.5700
            14  O2a O    30.7300  -17.5700
            15  C1a C    31.9200  -19.6700
            16  C1x C    23.4500  -16.1700
            17  C1x C    22.2600  -18.2700
            18  C1a C    31.9200  -18.2700
            19  C1x C    22.2600  -15.4700
            20  C1x C    21.0000  -17.5700
            21  N1y N    21.0000  -16.1700
            22  C5a C    19.8100  -15.4700
            23  C1y C    18.6200  -16.1700
            24  O5a O    19.8100  -14.0700
            25  C1x C    18.6200  -17.5700
            26  O2x O    17.2900  -15.7500
            27  C1x C    16.4500  -16.8700
            28  C1x C    17.2900  -17.9900
BOND        31
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 2
            8     4   9 1
            9     5  10 2
            10    6  11 2
            11    7  12 1
            12   10  13 1
            13   11  14 1
            14   12  15 1
            15   13  16 1
            16   13  17 1
            17   14  18 1
            18   16  19 1
            19   17  20 1
            20   19  21 1
            21    7  11 1
            22    8  10 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   22  24 2
            27   23  25 1
            28   23  26 1
            29   26  27 1
            30   27  28 1
            31   25  28 1

» Japanese version   » Back

DBGET integrated database retrieval system