KEGG   DRUG: D08578Help
Entry
D08578                      Drug                                   

Name
Tetryzoline (INN);
Tetrahydrozoline;
Caltheon (TN)
Formula
C13H16N2
Exact mass
200.1313
Mol weight
200.2795
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Vasoconstrictor ORL, local
Remark
Same as: 
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor agonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AA Sympathomimetics, plain
     R01AA06 Tetryzoline
      D08578  Tetryzoline (INN)
    R01AB Sympathomimetics, combinations excl. corticosteroids
     R01AB03 Tetryzoline
      D08578  Tetryzoline (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01G DECONGESTANTS AND ANTIALLERGICS
    S01GA Sympathomimetics used as decongestants
     S01GA02 Tetryzoline
      D08578  Tetryzoline (INN)
USP drug classification [BR:br08302]
 Respiratory Tract/Pulmonary Agents
  Respiratory Tract Agents, Other
   Tetrahydrozoline
    D08578  Tetryzoline (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Tetryzoline
    D08578  Tetryzoline (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Tetryzoline
      D08578  Tetryzoline (INN)
BRITE hierarchy
Other DBs
CAS: 
84-22-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        15
            1   C8x C    16.2400  -18.6900
            2   C8x C    16.2400  -17.2900
            3   C8x C    17.5000  -16.5900
            4   C8y C    18.6900  -17.2900
            5   C8y C    18.6900  -18.6900
            6   C8x C    17.5000  -19.3900
            7   C1y C    19.8800  -16.5900
            8   C1x C    21.0700  -17.2900
            9   C1x C    21.0700  -18.6900
            10  C1x C    19.8800  -19.3900
            11  C2y C    19.8800  -15.1200
            12  N2x N    18.7600  -14.2800
            13  C1x C    19.1800  -12.9500
            14  C1x C    20.5800  -12.9500
            15  N1x N    21.0000  -14.2800
BOND        17
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    7  11 1
            13   11  12 2
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   11  15 1

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