KEGG   DRUG: D08598Help
Entry
D08598                      Drug                                   

Name
Tilisolol (INN)
Formula
C17H24N2O3
Exact mass
304.1787
Mol weight
304.3841
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
beta-Adrenergic blocking
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Tilisolol
      D08598  Tilisolol (INN)
    beta2-adrenergic receptor
     Tilisolol
      D08598  Tilisolol (INN)
    beta3-adrenergic receptor
     Tilisolol
      D08598  Tilisolol (INN)
BRITE hierarchy
Other DBs
CAS: 
85136-71-6
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8x C    17.9900  -19.6700
            2   C8x C    17.9900  -18.2700
            3   C8x C    19.1800  -17.5700
            4   C8x C    19.1800  -20.3700
            5   C8y C    20.3700  -19.6700
            6   C8y C    20.3700  -18.2700
            7   C8y C    21.6300  -17.5700
            8   C8x C    22.8200  -18.2700
            9   N4y N    22.8200  -19.6700
            10  C8y C    21.6300  -20.3700
            11  O5x O    21.6300  -21.7700
            12  O2a O    21.6300  -16.1700
            13  C1b C    22.8200  -15.4700
            14  C1c C    24.0100  -16.1700
            15  C1b C    25.2700  -15.4700
            16  N1b N    26.4600  -16.1700
            17  C1d C    27.6500  -15.5400
            18  O1a O    24.0100  -17.5700
            19  C1a C    27.6500  -14.1400
            20  C1a C    28.9100  -16.2400
            21  C1a C    28.9100  -14.8400
            22  C1a C    24.0800  -20.3700
BOND        23
            1     4   1 1
            2    10  11 2
            3     7  12 1
            4    12  13 1
            5     1   2 2
            6    13  14 1
            7     2   3 1
            8    14  15 1
            9     3   6 2
            10   15  16 1
            11    5   4 2
            12   16  17 1
            13    5   6 1
            14   14  18 1
            15    6   7 1
            16   17  19 1
            17    7   8 2
            18   17  20 1
            19    8   9 1
            20   17  21 1
            21    9  10 1
            22    9  22 1
            23   10   5 1

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