| Entry |
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| Name |
Tirofiban (INN);
Agrastat (TN)
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| Formula |
C22H36N2O5S
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| Exact mass |
440.2345
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| Mol weight |
440.5966
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| Structure |
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| Activity |
Anticoagulant, platelet aggregation inhibitor
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| Remark |
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| Comment |
Indication: Acute coronary syndrome
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC17 Tirofiban
D08607 Tirofiban (INN)
Target-based classification of drugs [BR:br08310]
Others
Cell adhesion molecules (CAMs)
glycoprotein alpha IIb/beta3 (GPIIb/IIIa) receptor [HSA:3674 3690] [KO:K06476 K06493]
Tirofiban [ATC:B01AC17]
D08607 Tirofiban (INN)
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| Other DBs |
CAS: 144494-65-5 PubChem: DrugBank: PDB-CCD: LigandBox: |
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| KCF data |
ATOM 30
1 C8y C 16.8671 -15.7324
2 C1b C 15.6736 -15.0303
3 C8x C 16.8673 -17.1366
4 C8x C 18.0607 -15.0303
5 C1c C 14.4098 -15.7324
6 C8x C 18.0607 -17.8387
7 C8x C 19.2543 -15.7324
8 N1b N 14.4098 -17.1366
9 C6a C 13.2162 -15.0303
10 C8y C 19.2543 -17.1366
11 S4a S 13.2864 -17.9089
12 O6a O 12.0227 -15.7324
13 O6a O 13.2162 -13.6262
14 O2a O 20.5180 -17.8387
15 C1b C 12.0227 -17.1366
16 O3c O 14.4800 -18.7515
17 O3c O 12.1631 -18.7515
18 C1b C 21.7116 -17.1366
19 C1b C 10.8291 -17.8387
20 C1b C 22.9052 -17.8387
21 C1b C 9.5653 -17.1366
22 C1b C 24.0987 -17.1366
23 C1a C 8.3717 -17.8387
24 C1b C 25.3625 -17.8387
25 C1y C 26.5561 -17.1366
26 C1x C 27.7496 -17.8387
27 C1x C 26.5561 -15.7324
28 C1x C 28.9432 -17.1366
29 C1x C 27.7496 -15.0303
30 N1x N 28.9432 -15.7324
BOND 31
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 2
7 5 8 1 #Down
8 5 9 1
9 6 10 2
10 8 11 1
11 9 12 1
12 9 13 2
13 10 14 1
14 11 15 1
15 11 16 2
16 11 17 2
17 14 18 1
18 15 19 1
19 18 20 1
20 19 21 1
21 20 22 1
22 21 23 1
23 22 24 1
24 24 25 1
25 25 26 1
26 25 27 1
27 26 28 1
28 27 29 1
29 28 30 1
30 7 10 1
31 29 30 1
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