KEGG   DRUG: D08645Help
Entry
D08645                      Drug                                   

Name
Tripelennamine (INN)
Formula
C16H21N3
Exact mass
255.1735
Mol weight
255.358
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
Same as: 
ATC code: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
CYP inhibition: CYP2D6 [HSA:1565]
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
   D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
    D04AA Antihistamines for topical use
     D04AA04 Tripelennamine
      D08645  Tripelennamine (INN)
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AC Substituted ethylene diamines
     R06AC04 Tripelennamine
      D08645  Tripelennamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor [HSA:3269] [KO:K04149]
     Tripelennamine [ATC:D04AA04]
      D08645  Tripelennamine (INN)
BRITE hierarchy
Other DBs
CAS: 
91-81-6
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C8x C    19.3200  -16.9400
            2   C8x C    19.3200  -18.3400
            3   C8x C    20.5800  -19.0400
            4   C8x C    21.7700  -18.3400
            5   C8y C    21.7700  -16.9400
            6   C8x C    20.5800  -16.2400
            7   N5x N    22.9600  -19.0400
            8   C8y C    24.2200  -18.3400
            9   N1c N    24.2200  -16.9400
            10  C1b C    22.9600  -16.2400
            11  C8x C    22.9600  -20.4400
            12  C8x C    24.2200  -21.1400
            13  C8x C    25.4100  -20.4400
            14  C8x C    25.4100  -19.0400
            15  C1b C    25.4100  -16.2400
            16  C1b C    26.6000  -16.8700
            17  N1c N    27.7900  -16.2400
            18  C1a C    28.9800  -16.8700
            19  C1a C    27.7900  -14.7700
BOND        20
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     9  10 1
            10    5  10 1
            11    7  11 2
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15    8  14 2
            16    9  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   17  19 1

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