KEGG   DRUG: D08648Help
Entry
D08648                      Drug                                   

Name
Triprolidine (INN)
Formula
C19H22N2
Exact mass
278.1783
Mol weight
278.3914
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX07 Triprolidine
      D08648  Triprolidine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Triprolidine
    D08648  Triprolidine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Triprolidine
      D08648  Triprolidine (INN)
BRITE hierarchy
Other DBs
CAS: 
486-12-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C2b C    24.7800  -17.9900
            2   C1b C    23.5200  -17.2900
            3   N1y N    23.5200  -15.8900
            4   C1x C    22.4000  -15.0500
            5   C1x C    22.8200  -13.7200
            6   C1x C    24.2200  -13.7200
            7   C1x C    24.6400  -15.0500
            8   C8x C    21.1400  -20.0900
            9   C8y C    21.1400  -21.4900
            10  C8x C    22.3300  -22.1900
            11  C8x C    23.5200  -21.4900
            12  C8y C    23.5200  -20.0900
            13  C8x C    22.3300  -19.3900
            14  C2c C    24.7800  -19.3900
            15  C8y C    25.9700  -20.0900
            16  C8x C    25.9700  -21.4900
            17  C8x C    27.1600  -22.1900
            18  C8x C    28.4200  -21.4900
            19  C8x C    28.4200  -20.0900
            20  N5x N    27.1600  -19.3900
            21  C1a C    19.8800  -22.1900
BOND        23
            1     3   4 1
            2     8   9 2
            3     9  10 1
            4    10  11 2
            5    11  12 1
            6    12  13 2
            7    13   8 1
            8     4   5 1
            9    12  14 1
            10    5   6 1
            11   14  15 1
            12    6   7 1
            13    7   3 1
            14    2   3 1
            15   15  16 2
            16   16  17 1
            17   17  18 2
            18   18  19 1
            19   19  20 2
            20   20  15 1
            21    1   2 1
            22    9  21 1
            23   14   1 2

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