KEGG   DRUG: D08662Help
Entry
D08662                      Drug                                   

Name
Urapidil hydrochloride;
Ebrantil (TN)
Formula
C20H29N5O3. HCl
Exact mass
423.2037
Mol weight
423.9369
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
ATC code: 
Drug group: 
Target
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02C ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
    C02CA Alpha-adrenoreceptor antagonists
     C02CA06 Urapidil
      D08662  Urapidil hydrochloride
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Urapidil
      D08662  Urapidil hydrochloride
BRITE hierarchy
Other DBs
CAS: 
64887-14-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        29
            1   C8x C    16.2400  -21.4200
            2   C8x C    16.2400  -20.0200
            3   C8y C    17.5000  -19.3200
            4   C8y C    18.6900  -20.0200
            5   C8x C    18.6900  -21.4200
            6   C8x C    17.5000  -22.1200
            7   N1y N    19.8800  -19.3200
            8   C1x C    19.8800  -17.9200
            9   C1x C    21.1400  -17.2200
            10  N1y N    22.3300  -17.9200
            11  C1x C    22.3300  -19.3200
            12  C1x C    21.1400  -20.0200
            13  C1b C    23.5200  -17.2200
            14  C1b C    24.7800  -17.9200
            15  C1b C    25.9700  -17.2200
            16  N1b N    27.1600  -17.9200
            17  C8y C    28.4200  -17.2200
            18  C8x C    28.4200  -15.8200
            19  C8y C    29.6100  -15.1200
            20  N4y N    30.8000  -15.8200
            21  C8y C    30.8000  -17.2200
            22  N4y N    29.6100  -17.9200
            23  C1a C    29.6100  -19.3200
            24  O5x O    32.0600  -17.9200
            25  C1a C    32.0600  -15.1200
            26  O5x O    29.6100  -13.7200
            27  O2a O    17.5000  -17.9200
            28  C1a C    16.3100  -17.2200
            29  X   Cl   34.3000  -20.5100
BOND        30
            1    13  14 1
            2     4   7 1
            3    14  15 1
            4     1   2 2
            5    15  16 1
            6     2   3 1
            7    16  17 1
            8     3   4 2
            9     4   5 1
            10    5   6 2
            11    7   8 1
            12    8   9 1
            13   17  18 2
            14   18  19 1
            15   19  20 1
            16   20  21 1
            17   21  22 1
            18   22  17 1
            19    9  10 1
            20   22  23 1
            21   10  11 1
            22   21  24 2
            23   11  12 1
            24   20  25 1
            25   12   7 1
            26   19  26 2
            27    6   1 1
            28    3  27 1
            29   10  13 1
            30   27  28 1

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