KEGG   DRUG: D08664Help
Entry
D08664                      Drug                                   

Name
Valaciclovir (INN);
Valacyclovir;
Valtrex (TN)
Formula
C13H20N6O4
Exact mass
324.1546
Mol weight
324.3357
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [DS:H00365]
Remark
ATC code: 
Drug group: 
Comment
prodrug, active substance: Aciclovir [DR:D00222]
Target
DNA polymerase inhibitor
Metabolism
Transporter: SLC15A1 [HSA:6564], SCL15A2 [HSA:6565]
Interaction
Drug interaction
Structure map
Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB11 Valaciclovir
      D08664  Valaciclovir (INN)
USP drug classification [BR:br08302]
 Antivirals
  Antiherpetic Agents
   Valacyclovir
    D08664  Valaciclovir (INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HSV agents
   DNA polymerase inhibitor
    Purine analogue
     Valacyclovir
      D08664  Valaciclovir (INN)
BRITE hierarchy
Other DBs
CAS: 
124832-26-4
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   N4y N    23.8700  -17.9200
            2   C8y C    25.1300  -17.4300
            3   C8y C    25.1300  -16.0300
            4   N5x N    23.8000  -15.6800
            5   C8x C    23.0300  -16.8000
            6   N5x N    26.3900  -18.1300
            7   C8y C    27.5800  -17.4300
            8   N4x N    27.5800  -16.0300
            9   C8y C    26.3200  -15.3300
            10  O5x O    26.3200  -13.9300
            11  N1a N    28.8400  -18.0600
            12  C1b C    23.8700  -19.3200
            13  O2a O    22.6100  -20.0200
            14  C1b C    21.4200  -19.3200
            15  C1b C    20.1600  -20.0200
            16  O7a O    18.9700  -19.3200
            17  C7a C    17.7519  -20.0101
            18  C1c C    16.5705  -19.3150
            19  C1c C    15.3651  -19.9980
            20  C1a C    14.1939  -19.3091
            21  C1a C    15.4231  -21.4192
            22  O6a O    17.8102  -21.4194
            23  N1a N    16.5819  -17.9200
BOND        24
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     1   5 1
            6     2   6 1
            7     6   7 2
            8     7   8 1
            9     8   9 1
            10    3   9 1
            11    9  10 2
            12    7  11 1
            13    1  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   19  21 1
            23   17  22 2
            24   18  23 1 #Down

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