KEGG   DRUG: D08866Help
Entry
D08866                      Drug                                   

Name
Baminercept (USAN/INN);
Baminercept alfa (USAN)
Formula
C4074H6282N1134O1274S68
Exact mass
93650.2648
Mol weight
93710.7243
Sequence
AVPPYASENQ TCRDQEKEYY EPQHRICCSR CPPGTYVSAK CSRIRDTVCA TCAENSYNEH
WNYLTICQLC RPCDPVMGLE EIAPCTSKRK TQCRCQPGMF CAAWALECTH CELLSDCPPG
TEAELKDEVG KGNNHCVPCK AGHFQNTSSP SARCQPHTRC ENQGLVEAAP GTAQSDTTCK
NPLEPLPPEM SGTMVDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD
VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN
KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG
QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP
G
(Disulfide bridge: 12-27; 28-41; 31-49; 52-67; 70-85; 73-93; 95-101; 108-117; 111-136; 139-154; 160-179; 236-296; 342-400, Dimer: 201; 204)
  Type
Peptide
Activity
Treatment of rheumatoid arthritis
Comment
Fusion protein
Target
lymphotoxin beta [HSA:4050] [KO:K03157]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04064  NF-kappa B signaling pathway
hsa05323  Rheumatoid arthritis  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   LTB
    Baminercept
     D08866  Baminercept (USAN/INN); Baminercept alfa (USAN)
BRITE hierarchy
Other DBs
CAS: 
909110-25-4
PubChem: 

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