KEGG   DRUG: D08892Help
Entry
D08892                      Drug                                   

Name
Clevidipine (USAN/INN);
Clevidipine butyrate;
Cleviprex (TN)
Product
Formula
C21H23Cl2NO6
Exact mass
455.0902
Mol weight
456.3164
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
ATC code: 
Drug group: 
Target
L-type calcium channel blocker [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  Pathway
hsa04020  Calcium signaling pathway
hsa04260  Cardiac muscle contraction
hsa04270  Vascular smooth muscle contraction  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C08 CALCIUM CHANNEL BLOCKERS
   C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
    C08CA Dihydropyridine derivatives
     C08CA16 Clevidipine
      D08892  Clevidipine (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Ca2+ channel, CACN alpha-1, CaVx.x
    calcium channel L type
     Clevidipine
      D08892  Clevidipine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
167221-71-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   C2y C    22.3404  -13.2197
            2   C2y C    22.3404  -14.6377
            3   C1y C    23.5685  -15.3468
            4   C2y C    24.7966  -14.6377
            5   C2y C    24.7966  -13.2197
            6   N1x N    23.5685  -12.5106
            7   C1a C    26.0436  -12.4995
            8   C1a C    21.1124  -12.5106
            9   C7a C    26.0501  -15.3468
            10  O7a O    27.2783  -14.6377
            11  C1b C    28.5063  -15.3468
            12  O7a O    29.7344  -14.6377
            13  C7a C    30.9625  -15.3468
            14  C1b C    32.1906  -14.6377
            15  C1b C    33.4186  -15.3468
            16  C1a C    34.6468  -14.6377
            17  C7a C    21.1124  -15.3468
            18  O7a O    19.9015  -14.6475
            19  O6a O    21.1123  -16.7646
            20  O6a O    26.0564  -16.4100
            21  O6a O    30.9625  -16.7645
            22  C1a C    18.6987  -15.3418
            23  C8y C    23.5685  -16.7646
            24  C8x C    22.3234  -17.4836
            25  C8x C    22.3235  -18.9017
            26  C8x C    23.5517  -19.6106
            27  C8y C    24.7967  -18.8916
            28  C8y C    24.7966  -17.4736
            29  X   Cl   26.0438  -19.6117
            30  X   Cl   25.9537  -17.4611
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     5   7 1
            8     1   8 1
            9     4   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17    2  17 1
            18   17  18 1
            19   17  19 2
            20    9  20 2
            21   13  21 2
            22   18  22 1
            23    3  23 1
            24   23  24 2
            25   24  25 1
            26   25  26 2
            27   26  27 1
            28   27  28 2
            29   23  28 1
            30   27  29 1
            31   28  30 1

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