KEGG   DRUG: D08949Help
Entry
D08949                      Drug                                   

Name
Naveglitazar (USAN/INN)
Formula
C25H26O6
Exact mass
422.1729
Mol weight
422.4703
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of Type II diabetes and associated cardiovascular indications
Target
peroxisome proliferator-activated receptor (PPAR) alpha agonist [HSA:5465] [KO:K07294]
  Pathway
hsa03320  PPAR signaling pathway
hsa04920  Adipocytokine signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) alpha
     Naveglitazar
      D08949  Naveglitazar (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
476436-68-7
PubChem: 
LigandBox: 
KCF data Show

ATOM        31
            1   C8x C    21.8400  -20.1600
            2   C8y C    21.8400  -21.5600
            3   C8x C    23.0524  -22.2600
            4   C8x C    24.2649  -21.5600
            5   C8y C    24.2649  -20.1600
            6   C8x C    23.0524  -19.4600
            7   O2a O    20.6276  -22.2600
            8   C1b C    19.4321  -21.5696
            9   C1b C    18.2447  -22.2551
            10  C1b C    17.0535  -21.5671
            11  O2a O    15.8640  -22.2538
            12  C8y C    14.6739  -21.5665
            13  C1b C    25.4960  -19.4490
            14  C1c C    26.7012  -20.1447
            15  C6a C    27.8835  -19.4619
            16  O6a O    29.0775  -20.1512
            17  O6a O    27.8835  -18.0602
            18  O2a O    26.7016  -21.5596
            19  C1a C    27.8905  -22.2459
            20  C8x C    14.6739  -20.1602
            21  C8x C    13.4615  -19.4602
            22  C8y C    12.2491  -20.1601
            23  C8x C    12.2490  -21.5663
            24  C8x C    13.4614  -22.2664
            25  O2a O    11.0373  -19.4604
            26  C8y C     9.8422  -20.1505
            27  C8x C     8.6547  -19.4649
            28  C8x C     7.4423  -20.1649
            29  C8x C     7.4422  -21.5649
            30  C8x C     8.6297  -22.2505
            31  C8x C     9.8421  -21.5505
BOND        33
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    5  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   15  17 2
            18   14  18 1 #Up
            19   18  19 1
            20   12  20 2
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   12  24 1
            26   22  25 1
            27   25  26 1
            28   26  27 2
            29   27  28 1
            30   28  29 2
            31   29  30 1
            32   30  31 2
            33   26  31 1

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