| Entry |
|
|---|
| Name |
Naveglitazar (USAN/INN)
|
|---|
| Formula |
C25H26O6
|
|---|
| Exact mass |
422.1729
|
|---|
| Mol weight |
422.4703
|
|---|
| Structure |
     |
|---|
| Activity |
Treatment of Type II diabetes and associated cardiovascular indications
|
|---|
| Target |
peroxisome proliferator-activated receptor (PPAR) alpha agonist [HSA: 5465] [KO: K07294] |
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
peroxisome proliferator-activated receptor (PPAR) alpha [HSA:5465] [KO:K07294]
Naveglitazar
D08949 Naveglitazar (USAN/INN)
 |
|---|
| Other DBs |
CAS: 476436-68-7 PubChem: LigandBox: |
|---|
| KCF data |
ATOM 31
1 C1b C 24.1500 -14.9800
2 C8y C 16.8700 -13.5800
3 C8x C 16.8700 -14.9800
4 C8x C 18.0600 -15.6800
5 C8y C 19.3200 -14.9800
6 C8x C 19.3200 -13.5800
7 C8x C 18.0600 -12.8800
8 C1b C 15.6800 -12.8800
9 C1c C 14.4200 -13.5800
10 O2a O 20.5100 -15.6800
11 C1b C 21.7000 -14.9800
12 C1b C 22.9153 -15.6751
13 O2a O 25.3547 -15.6932
14 C8y C 26.5690 -15.0095
15 C8x C 27.7831 -15.7285
16 C8x C 29.0032 -15.0419
17 C8y C 29.0187 -13.6420
18 C8x C 27.8046 -12.9230
19 C8x C 26.5845 -13.6096
20 O2a O 30.2588 -12.9438
21 C8y C 31.4523 -13.6503
22 C8x C 31.4370 -15.0500
23 C8x C 32.6417 -15.7632
24 C8x C 33.8617 -15.0765
25 C8x C 33.8770 -13.6768
26 C8x C 32.6723 -12.9636
27 C6a C 13.2193 -12.8601
28 O2a O 14.3969 -14.9798
29 C1a C 13.1908 -15.6501
30 O6a O 11.9954 -13.5401
31 O6a O 13.2422 -11.4801
BOND 33
1 2 3 2
2 3 4 1
3 4 5 2
4 5 6 1
5 6 7 2
6 2 7 1
7 2 8 1
8 8 9 1
9 5 10 1
10 10 11 1
11 11 12 1
12 1 12 1
13 1 13 1
14 13 14 1
15 14 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 14 19 1
21 17 20 1
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 24 25 1
27 25 26 2
28 21 26 1
29 9 27 1
30 9 28 1 #Down
31 28 29 1
32 27 30 1
33 27 31 2
|
|---|
