KEGG   DRUG: D08966Help
Entry
D08966                      Drug                                   

Name
Phenylephrine bitartrate (USP)
Formula
C9H13NO2. C4H6O6
Exact mass
317.1111
Mol weight
317.2919
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
alpha-Sympathomimetic
Remark
Comment
See [DR:D08366]
Target
alpha1-adrenergic receptor agonist [HSA:146 147 148] [KO:K04137 K04136 K04135]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA06 Phenylephrine
      D08966  Phenylephrine bitartrate (USP)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AA Sympathomimetics, plain
     R01AA04 Phenylephrine
      D08966  Phenylephrine bitartrate (USP)
    R01AB Sympathomimetics, combinations excl. corticosteroids
     R01AB01 Phenylephrine
      D08966  Phenylephrine bitartrate (USP)
   R01B NASAL DECONGESTANTS FOR SYSTEMIC USE
    R01BA Sympathomimetics
     R01BA03 Phenylephrine
      D08966  Phenylephrine bitartrate (USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FB Sympathomimetics excl. antiglaucoma preparations
     S01FB01 Phenylephrine
      D08966  Phenylephrine bitartrate (USP)
   S01G DECONGESTANTS AND ANTIALLERGICS
    S01GA Sympathomimetics used as decongestants
     S01GA05 Phenylephrine
      D08966  Phenylephrine bitartrate (USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Alpha-adrenergic Agonists
   Phenylephrine
    D08966  Phenylephrine bitartrate (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Phenylephrine
      D08966  Phenylephrine bitartrate (USP)
BRITE hierarchy
Other DBs
CAS: 
17162-39-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   O6a O    20.8287  -16.4689
            2   C6a C    22.0425  -15.7681
            3   C1c C    23.2564  -16.4689
            4   C1c C    24.4702  -15.7681
            5   C6a C    25.6840  -16.4689
            6   O6a O    26.8979  -15.7681
            7   O6a O    22.0425  -14.3667
            8   O6a O    25.6840  -17.8704
            9   O1a O    23.2564  -17.8703
            10  O1a O    24.4702  -14.3665
            11  C8y C    10.0800  -16.4500
            12  C8x C    10.0800  -17.8500
            13  C8x C    11.2700  -18.5500
            14  C8x C    12.4600  -17.8500
            15  C8y C    12.4600  -16.4500
            16  C8x C    11.2700  -15.7500
            17  O1a O     8.8200  -15.7500
            18  C1c C    13.7200  -15.7500
            19  C1b C    14.9100  -16.4500
            20  O1a O    13.7200  -14.3500
            21  N1b N    16.1000  -15.7500
            22  C1a C    17.2900  -16.4500
BOND        21
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     2   7 2
            7     5   8 2
            8     3   9 1 #Up
            9     4  10 1 #Up
            10   11  12 2
            11   12  13 1
            12   13  14 2
            13   14  15 1
            14   15  16 2
            15   11  16 1
            16   11  17 1
            17   15  18 1
            18   18  19 1
            19   18  20 1 #Up
            20   19  21 1
            21   21  22 1

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