KEGG   DRUG: D08990Help
Entry
D08990                      Drug                                   

Name
Romiplostim (genetical recombination) (JAN);
Romiplostim (USAN/INN);
Nplate (TN);
Romiplate (TN)
Product
Formula
C1317H2043N361O395S9
Exact mass
29523.8362
Mol weight
29542.08
Activity
Treatment of immune thrombocytopenic purpura [ITP] [DS:H01240]
Remark
Therapeutic category: 
ATC code: 
Comment
Fusion protein (Thrombopoietin-binding peptide fused to Fc of human IgG1)
Target
thrombopoietin receptor agonist [HSA:4352] [KO:K05082]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BX Other systemic hemostatics
     B02BX04 Romiplostim
      D08990  Romiplostim (genetical recombination) (JAN); Romiplostim (USAN/INN)
USP drug classification [BR:br08302]
 Blood Products/Modifiers/Volume Expanders
  Blood Formation Modifiers
   Romiplostim
    D08990  Romiplostim (genetical recombination) (JAN); Romiplostim (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D08990  Romiplostim (genetical recombination) (JAN); Romiplostim (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   thrombopoietin receptor
    Romiplostim
     D08990  Romiplostim (genetical recombination) (JAN); Romiplostim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
267639-76-9
PubChem: 

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