KEGG   DRUG: D09008Help
Entry
D09008                      Drug                                   

Name
Talaglumetad hydrochloride (USAN)
Formula
C11H16N2O5. HCl
Exact mass
292.0826
Mol weight
292.7161
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of anxiety and stress disorders [metabotropic glutamate [mGlu] agonist]
Target
metabotropic glutamate receptor (mGlu) 2/3 agonist [HSA:2912 2913] [KO:K04605]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Metabotropic glutamate receptor family
   Glutamate (metabotropic)
    metabotropic glutamate receptor 2/3 [HSA:2912 2913] [KO:K04605]
     Talaglumetad
      D09008  Talaglumetad hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
441765-97-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        19
            1   C1y C    23.0668  -17.7924
            2   C1y C    23.0668  -19.1869
            3   C1z C    24.3916  -19.6750
            4   C1x C    25.2283  -18.4897
            5   C1x C    24.3916  -17.3740
            6   C1y C    21.8117  -18.4897
            7   C6a C    20.4869  -18.4897
            8   O6a O    19.7896  -17.3043
            9   O6a O    19.7896  -19.7447
            10  C6a C    25.5770  -20.3723
            11  N1b N    24.3916  -21.0696
            12  O6a O    26.7623  -19.6750
            13  O6a O    25.5770  -21.7668
            14  C5a C    23.1839  -21.7668
            15  C1c C    23.1839  -23.1614
            16  C1a C    21.9931  -23.8491
            17  O5a O    21.9931  -21.0791
            18  N1a N    24.4082  -23.8684
            19  X   Cl   30.3184  -20.2328
BOND        19
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     1   6 1
            7     2   6 1
            8     6   7 1 #Up
            9     7   8 1
            10    7   9 2
            11    3  10 1 #Up
            12    3  11 1 #Down
            13   10  12 1
            14   10  13 2
            15   11  14 1
            16   14  15 1
            17   15  16 1
            18   14  17 2
            19   15  18 1 #Up

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