KEGG   DRUG: D09205Help
Entry
D09205                      Drug                                   

Name
Prucalopride (USAN/INN)
Formula
C18H26ClN3O3
Exact mass
367.1663
Mol weight
367.8703
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of constipation
Remark
ATC code: 
Target
5-HT4-receptor agonist [HSA:3360] [KO:K04160]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A06 DRUGS FOR CONSTIPATION
   A06A DRUGS FOR CONSTIPATION
    A06AX Other drugs for constipation
     A06AX05 Prucalopride
      D09205  Prucalopride (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor [HSA:3360] [KO:K04160]
     Prucalopride [ATC:A03AE04]
      D09205  Prucalopride (INN)
BRITE hierarchy
Other DBs
CAS: 
179474-81-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        25
            1   C8y C    11.2000  -19.6700
            2   C8y C    11.2000  -21.0700
            3   C8y C    12.4124  -21.7700
            4   C8y C    13.6249  -21.0700
            5   C8y C    13.6249  -19.6700
            6   C8x C    12.4124  -18.9700
            7   C1x C    12.9135  -23.1394
            8   C1x C    14.3059  -23.1458
            9   O2x O    14.7353  -21.9368
            10  N1a N     9.9876  -21.7700
            11  X   Cl    9.9876  -18.9700
            12  C5a C    14.8560  -18.9590
            13  N1b N    16.0612  -19.6547
            14  O5a O    14.8557  -17.5701
            15  C1y C    17.2435  -18.9719
            16  C1x C    18.4375  -19.6612
            17  C1x C    19.6499  -18.9612
            18  N1y N    19.6499  -17.5612
            19  C1x C    18.4560  -16.8719
            20  C1x C    17.2435  -17.5719
            21  C1b C    20.8734  -16.8546
            22  C1b C    22.0824  -17.5525
            23  C1b C    23.2629  -16.8708
            24  O2a O    24.4578  -17.5607
            25  C1a C    25.6453  -16.8750
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     3   7 1
            8     7   8 1
            9     8   9 1
            10    4   9 1
            11    2  10 1
            12    1  11 1
            13    5  12 1
            14   12  13 1
            15   12  14 2
            16   13  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   15  20 1
            23   18  21 1
            24   21  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 1

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