KEGG   DRUG: UstekinumabHelp
Entry
D09214                      Drug                                   

Name
Ustekinumab (USAN/INN);
Ustekinumab (genetical recombination) (JAN);
Stelara (TN)
Product
Formula
C6482H10004N1712O2016S46
Exact mass
145556.0074
Mol weight
145646.04
Class
Other
 DG02019  Interleukin inhibitor
Remark
Therapeutic category: 
ATC code: 
Activity
Antipsoriatic, Anti-IL12/IL23 antibody
  Disease
Psoriasis [DS:H01656]
Psoriatic arthritis [DS:H01656]
Crohn's disease [DS:H00286]
Comment
Treatment of immunologically mediated inflammatory disorders
Monoclonal antibody
Target
IL12 [HSA:3592 3593] [KO:K05406 K05425];
IL23 [HSA:51561] [KO:K05426]
  Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AC Interleukin inhibitors
     L04AC05 Ustekinumab
      D09214  Ustekinumab (USAN/INN)
USP drug classification [BR:br08302]
 Dermatological Agents
  Ustekinumab
   D09214  Ustekinumab (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D09214  Ustekinumab (USAN/INN); Ustekinumab (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines
  Class I cytokines
   IL-12
    Ustekinumab
     D09214  Ustekinumab (USAN/INN)
   IL-23
    Ustekinumab
     D09214  Ustekinumab (USAN/INN)
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D09214
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09214
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09214
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09214
BRITE hierarchy
Other DBs
CAS: 
815610-63-0
PubChem: 

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