KEGG   DRUG: EtaracizumabHelp
Entry
D09342                      Drug                                   

Name
Etaracizumab (USAN/INN);
Abegrin (TN)
Formula
C6392H9908N1732O1996S42
Exact mass
144211.5312
Mol weight
144300.2007
Efficacy
Antineoplastic, Angiogenesis inhibitor, Anti-alpha-v-beta-3 antibody
Comment
Monoclonal antibody
Treatment of metastatic melanoma, prostate cancer
Target
ITGAV/ITGB3 [HSA:3685 3690] [KO:K06487 K06493]
  Pathway
hsa04510  Focal adhesion
hsa04512  ECM-receptor interaction
hsa04810  Regulation of actin cytoskeleton
Brite
Target-based classification of drugs [BR:br08310]
 Monoclonal antibodies
  ITGAV (CD51) / ITGB3 (CD61)
   Etaracizumab
    D09342  Etaracizumab (USAN/INN)
 Others
  Other
   integrin alphaV/beta3 (VNR)
    Etaracizumab
     D09342  Etaracizumab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 892553-42-3
PubChem: 96026022

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