KEGG   DRUG: D09366Help
Entry
D09366                      Drug                                   

Name
Pardoprunox hydrochloride (USAN)
Formula
C12H15N3O2. HCl
Exact mass
269.0931
Mol weight
269.7273
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Parkinson's disease, restless legs syndrome
Remark
Drug group: 
Target
dopamine D2-receptor partial agonist [HSA:1813] [KO:K04145];
dopamine D3-receptor partial agonist [HSA:1814] [KO:K04146];
5-HT1A-receptor agonist [HSA:3350] [KO:K04153]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D2-receptor
     Pardoprunox
      D09366  Pardoprunox hydrochloride (USAN)
    dopamine D3-receptor
     Pardoprunox
      D09366  Pardoprunox hydrochloride (USAN)
   Serotonin
    5-HT1A-receptor
     Pardoprunox
      D09366  Pardoprunox hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
269718-83-4
PubChem: 
LigandBox: 
KCF data Show

ATOM        18
            1   C1x C    19.1800  -22.8200
            2   N1y N    19.1800  -21.4200
            3   C1x C    20.4400  -20.7200
            4   C1x C    21.6300  -21.4200
            5   N1y N    21.6300  -22.8200
            6   C1x C    20.4400  -23.5200
            7   C8y C    22.8900  -23.5200
            8   C8y C    24.0800  -22.8200
            9   C8y C    25.2700  -23.5200
            10  C8x C    25.2700  -24.9200
            11  C8x C    24.0800  -25.6200
            12  C8x C    22.8900  -24.9200
            13  O7x O    24.3600  -21.4200
            14  C8y C    25.7600  -21.2800
            15  N4x N    26.3200  -22.5400
            16  O6a O    26.4600  -20.0900
            17  C1a C    17.9900  -20.7200
            18  X   Cl   29.2600  -21.9800
BOND        19
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13    7  12 2
            14    8  13 1
            15   13  14 1
            16   14  15 1
            17    9  15 1
            18   14  16 2
            19    2  17 1

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