KEGG   DRUG: D09368Help
Entry
D09368                      Drug                                   

Name
Pozanicline tartrate (USAN)
Formula
C11H16N2O. C4H6O6
Exact mass
342.1427
Mol weight
342.3444
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Attention deficit/hyperactivity disorder (ADHD);
dementia of the Alzheimer's type (AD)
Target
nicotinic cholinergic receptor alpha4beta2 partial agonist [HSA:1137 1141] [KO:K04806 K04813]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   Acetylcholine (nicotinic)
    alpha4beta2 nicotinic receptor
     Pozanicline
      D09368  Pozanicline tartrate (USAN)
BRITE hierarchy
Other DBs
CAS: 
945405-37-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        24
            1   C8y C    19.4197  -24.4214
            2   C8x C    19.4197  -25.8249
            3   C8x C    18.2268  -26.5266
            4   C8x C    16.9636  -25.8249
            5   N5x N    16.9636  -24.4214
            6   C8y C    18.2268  -23.7196
            7   O2a O    20.6127  -23.7196
            8   C1b C    21.8057  -24.4214
            9   C1y C    22.9986  -23.7196
            10  C1x C    23.4197  -22.3863
            11  C1x C    24.8232  -22.3863
            12  C1x C    25.2442  -23.7196
            13  N1x N    24.1214  -24.5617
            14  C1a C    18.2268  -22.3161
            15  C6a C    28.5425  -23.7196
            16  O6a O    27.3270  -24.4214
            17  C1c C    29.7726  -24.4298
            18  C1c C    30.9679  -23.7395
            19  C6a C    32.1553  -24.4250
            20  O6a O    33.3465  -23.7370
            21  O6a O    32.1555  -25.8298
            22  O6a O    28.5426  -22.3301
            23  O1a O    29.7727  -25.8298
            24  O1a O    30.9679  -22.3303
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     9   8 1 #Down
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13   9 1
            14   10   9 1
            15    6  14 1
            16   15  16 1
            17   15  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   19  21 2
            22   15  22 2
            23   17  23 1 #Up
            24   18  24 1 #Up

» Japanese version   » Back

DBGET integrated database retrieval system