KEGG   DRUG: D09579Help
Entry
D09579                      Drug                                   

Name
Arhalofenate (USAN/INN)
Formula
C19H17ClF3NO4
Exact mass
415.0798
Mol weight
415.7908
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of type 2 diabetes;
Treatment of hyperuricemica in patients with gout
Target
peroxisome proliferator-activated receptor (PPAR) gamma agonist [HSA:5468] [KO:K08530]
  Pathway
hsa03320  PPAR signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) gamma
     Arhalofenate
      D09579  Arhalofenate (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
24136-23-0
PubChem: 
LigandBox: 
KCF data Show

ATOM        28
            1   C8y C    13.2594  -14.4186
            2   C8x C    13.2594  -15.8226
            3   C8x C    14.4753  -16.5246
            4   C8x C    15.6913  -15.8226
            5   C8y C    15.6913  -14.4186
            6   C8x C    14.4753  -13.7164
            7   O2a O    16.9260  -13.7055
            8   C1c C    18.1347  -14.4032
            9   C7a C    19.3205  -13.7183
            10  O7a O    20.5179  -14.4097
            11  O6a O    19.3205  -12.3126
            12  C8y C    18.1351  -15.8222
            13  C1b C    21.7092  -13.7217
            14  C1b C    22.9038  -14.4114
            15  N1b N    24.0967  -13.7226
            16  C5a C    25.2905  -14.4119
            17  C1a C    26.4839  -13.7228
            18  O5a O    25.2907  -15.8224
            19  C1d C    12.0434  -13.7164
            20  X   F    10.8273  -13.0144
            21  C8x C    16.8956  -16.5387
            22  C8x C    16.8963  -17.9427
            23  C8y C    18.1126  -18.6441
            24  C8x C    19.3522  -17.9277
            25  C8x C    19.3515  -16.5236
            26  X   Cl   18.1132  -20.0349
            27  X   F    12.7432  -12.5044
            28  X   F    11.3436  -14.9286
BOND        29
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1 #Up
            10    9  10 1
            11    9  11 2
            12    8  12 1
            13   10  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   16  18 2
            19    1  19 1
            20   19  20 1
            21   12  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   24  25 1
            26   12  25 2
            27   23  26 1
            28   19  27 1
            29   19  28 1

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