| Entry |
|
|---|
| Name |
Intetumumab (USAN/INN)
|
|---|
| Formula |
C6468H10008N1744O2006S40
|
|---|
| Exact mass |
145488.3555
|
|---|
| Mol weight |
145577.7523
|
|---|
| Sequence |
(Heavy chain) QVQLVESGGG VVQPGRSRRL SCAASGFTFS RYTMHWVRQA
PGKGLEWVAV ISFDGSNKYY VDSVKGRFTI SRDNSENTLY LQVNILRAED TAVYYCAREA
RGSYAFDIWG QGTMVTVSSA STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW
NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKKVEPK
SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY
VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK
AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL
DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK
(Disulfide bridge: 22-96; 146-202; 263-323; 369-427, Dimer: 228; 231)
(Light chain) EIVLTQSPAT LSLSPGERAT LSCRASQSVS SYLAWYQQKP
GQAPRLLIYD ASNRATGIPA RFSGSGSGTD FTLTISSLEP EDFAVYYCQQ RSNWPPFTFG
PGTKVDIKRT VAAPSVFIFP PSDEQLKSGT ASVVCLLNNF YPREAKVQWK VDNALQSGNS
QESVTEQDSK DSTYSLSSTL TLSKADYEKH KVYACEVTHQ GLSSPVTKSF NRGEC
(Disulfide bridge: 23-88; 135-195; H222-L215) |
|---|
| Type |
Peptide |
|---|
| Activity |
Treatment of solid tumors
|
|---|
| Comment |
Monoclonal antibody
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Others
Cellular antigens
CD51 (integrin alpha V) [HSA:3685] [KO:K06487]
Intetumumab
D09631 Intetumumab (USAN/INN)
 |
|---|
| Other DBs |
|
|---|
