KEGG   DRUG: D09698Help
Entry
D09698                      Drug                                   

Name
Vilazodone (USAN/INN)
Formula
C26H27N5O2
Exact mass
441.2165
Mol weight
441.5249
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant
Remark
ATC code: 
Target
5-HT1A-receptor partial agonist [HSA:3350] [KO:K04153];
serotonin transporter inhibitor [HSA:6532] [KO:K05037]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AX Other antidepressants
     N06AX24 Vilazodone
      D09698  Vilazodone (USAN/INN)
USP drug classification [BR:br08302]
 Antidepressants
  SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/Serotonin and Norepinephrine Reuptake Inhibitors)
   Vilazodone
    D09698  Vilazodone (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT1-receptor [HSA:3350 3351 3352 3354 3355] [KO:K04153]
     Vilazodone [ATC:N06AX24]
      D09698  Vilazodone (USAN/INN)
 Transporters
  Solute carrier family
   SLC6
    SLC6A4 (serotonin transporter) [HSA:6532] [KO:K05037]
     Vilazodone [ATC:N06AX24]
      D09698  Vilazodone (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
163521-12-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        33
            1   C8x C    22.3300  -18.2700
            2   C8y C    22.3300  -19.6700
            3   C8x C    23.5200  -20.3700
            4   C8y C    24.7800  -19.6700
            5   C8y C    24.7800  -18.2700
            6   C8x C    23.5200  -17.5700
            7   C8x C    26.1100  -20.0900
            8   C8y C    26.8800  -18.9700
            9   O2x O    26.1100  -17.8500
            10  N1y N    21.1400  -20.3700
            11  C1x C    19.9500  -19.6700
            12  C1x C    18.6900  -20.3700
            13  N1y N    18.6900  -21.7700
            14  C1x C    19.8800  -22.4700
            15  C1x C    21.1400  -21.7700
            16  C1b C    17.5000  -22.4700
            17  C1b C    16.3100  -21.7700
            18  C1b C    15.1200  -22.4700
            19  C1b C    13.9300  -21.7700
            20  C8y C    12.7400  -22.4700
            21  C8x C     9.2400  -20.1600
            22  C8x C     9.2400  -21.5600
            23  C8y C    10.4300  -22.2600
            24  C8y C    11.6900  -21.5600
            25  C8x C    11.6900  -20.1600
            26  C8y C    10.4300  -19.4600
            27  N4x N    10.7100  -23.6600
            28  C8x C    12.1100  -23.8000
            29  C5a C    28.2800  -18.9700
            30  N1a N    28.9800  -20.1824
            31  O5a O    28.9800  -17.7576
            32  C3b C    10.4300  -18.0600
            33  N3a N    10.4300  -16.6600
BOND        37
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    5   9 1
            11    2  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   10  15 1
            18   13  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   24  25 1
            27   25  26 2
            28   21  26 1
            29   23  27 1
            30   27  28 1
            31   28  20 2
            32   24  20 1
            33    8  29 1
            34   29  30 1
            35   29  31 2
            36   26  32 1
            37   32  33 3

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