KEGG   DRUG: Lenalidomide hydrateHelp
Entry
D09813                      Drug                                   

Name
Lenalidomide hydrate (JAN);
Revlimid (TN)
Formula
(C13H13N3O3)2. H2O
Exact mass
536.2019
Mol weight
536.5365
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Immunomodulator
  Disease
Multiple myeloma [DS:H00010]
Comment
Thalidomide [DR:D00754] derivative
Target
TNF-alpha [HSA:7124] [KO:K03156]
Interaction
Genomic biomarker: Chromosome-5q deletion
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L04 IMMUNOSUPPRESSANTS
   L04A IMMUNOSUPPRESSANTS
    L04AX Other immunosuppressants
     L04AX04 Lenalidomide
      D09813  Lenalidomide hydrate (JAN)
USP drug classification [BR:br08302]
 Antineoplastics
  Antiangiogenic Agents
   Lenalidomide
    D09813  Lenalidomide hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D09813  Lenalidomide hydrate (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   TNF-alpha
    Lenalidomide
     D09813  Lenalidomide hydrate (JAN)
Antineoplastics [br08340.html]
 D09813
BRITE hierarchy
Other DBs
PubChem: 
LigandBox: 
KCF data Show

ATOM        39
            1   C8x C    19.9500  -19.5300
            2   C8x C    19.9500  -20.9300
            3   C8x C    21.2100  -21.6300
            4   C8y C    22.4000  -20.9300
            5   C8y C    22.4000  -19.5300
            6   C8y C    21.2100  -18.8300
            7   C5x C    23.7300  -21.4200
            8   N1y N    24.5700  -20.2300
            9   C1x C    23.7300  -19.1100
            10  C1y C    25.9000  -20.2300
            11  O5x O    24.1500  -22.7500
            12  N1a N    21.2100  -17.4300
            13  C1x C    26.6700  -21.4900
            14  C1x C    28.0700  -21.4900
            15  C5x C    28.7700  -20.2300
            16  N1x N    28.0700  -19.0400
            17  C5x C    26.6700  -19.0400
            18  O5x O    25.9700  -17.8500
            19  O5x O    30.1700  -20.2300
            20  O0  O    35.2800  -20.7900
            21  C8x C    19.9500  -19.5300
            22  C8x C    19.9500  -20.9300
            23  C8x C    21.2100  -21.6300
            24  C8y C    22.4000  -20.9300
            25  C8y C    22.4000  -19.5300
            26  C8y C    21.2100  -18.8300
            27  N1a N    21.2100  -17.4300
            28  C1x C    23.7300  -19.1100
            29  N1y N    24.5700  -20.2300
            30  C5x C    23.7300  -21.4200
            31  O5x O    24.1500  -22.7500
            32  C1y C    25.9000  -20.2300
            33  C1x C    26.6700  -21.4900
            34  C1x C    28.0700  -21.4900
            35  C5x C    28.7700  -20.2300
            36  N1x N    28.0700  -19.0400
            37  C5x C    26.6700  -19.0400
            38  O5x O    25.9700  -17.8500
            39  O5x O    30.1700  -20.2300
BOND        42
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    5   9 1
            11    8  10 1
            12    7  11 2
            13    6  12 1
            14   10  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   10  17 1
            20   17  18 2
            21   15  19 2
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   24  25 1
            26   25  26 2
            27   21  26 1
            28   24  30 1
            29   30  29 1
            30   29  28 1
            31   25  28 1
            32   29  32 1
            33   30  31 2
            34   26  27 1
            35   32  33 1
            36   33  34 1
            37   34  35 1
            38   35  36 1
            39   36  37 1
            40   32  37 1
            41   37  38 2
            42   35  39 2
BRACKET     1    19.1800  -23.8700   19.1800  -16.3100
            1    31.0100  -16.3100   31.0100  -23.8700
            1  2
 ORIGINAL  1    1   2   3   4   5   6  12   9   8   7  11  10  13  14  15  16
            1   17  18  19
 REPEAT    1   21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36
            1   37  38  39

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