KEGG   DRUG: Chlorpromazine tannateHelp
Entry
D09819                      Drug                                   

Name
Chlorpromazine tannate (JAN)
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01465  alpha-Adrenergic receptor antagonist
   DG01460  alpha2-Adrenergic receptor antagonist
Neuropsychiatric agent
 DG01905  Phenothiazine antipsychotics
 DG01478  Dopamine antagonist
  DG01474  Dopamine D2-receptor antagonist
 DG01491  Muscarinic cholinergic receptor antagonist
Anti-allergic agent
 DG01557  Histamine receptor antagonist
  DG01482  Histamine receptor H1 antagonist
Cyp substrate
 DG01644  CYP2D6 substrate
Cyp inhibitor
 DG01645  CYP2D6 inhibitor
Remark
ATC code: 
Chemical group: 
Activity
Antipsychotic
Comment
Phenothiazine derivative
Target
5-HT2-receptor [HSA:3356 3357 3358] [KO:K04157];
H1-receptor [HSA:3269] [KO:K04149];
alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140];
dopamine D2-receptor [HSA:1813] [KO:K04145];
muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
Dopaminergic synapse
Metabolism
Enzyme: CYP2D6 [HSA:1565]
Interaction
CYP inhibition: CYP2D6 [HSA:1565]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AA Phenothiazines with aliphatic side-chain
     N05AA01 Chlorpromazine
      D09819  Chlorpromazine tannate (JAN)
USP drug classification [BR:br08302]
 Antiemetics
  Antiemetics, Other
   Chlorpromazine
    D09819  Chlorpromazine tannate (JAN)
 Antipsychotics
  1st Generation/Typical
   Chlorpromazine
    D09819  Chlorpromazine tannate (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Chlorpromazine
      D09819  Chlorpromazine tannate (JAN)
   Adrenaline
    alpha2-adrenergic receptor
     Chlorpromazine
      D09819  Chlorpromazine tannate (JAN)
   Dopamine
    dopamine D2-receptor
     Chlorpromazine
      D09819  Chlorpromazine tannate (JAN)
   Histamine
    H1-receptor
     Chlorpromazine
      D09819  Chlorpromazine tannate (JAN)
   Serotonin
    5-HT2-receptor
     Chlorpromazine
      D09819  Chlorpromazine tannate (JAN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP2D6
   Chlorpromazine
    D09819  Chlorpromazine tannate (JAN)
 CYP substrates
  CYP2D6
   Chlorpromazine
    D09819  Chlorpromazine tannate (JAN)
BRITE hierarchy
Other DBs
PubChem: 

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