| Entry |
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| Name |
Atopaxar hydrobromide (USAN)
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| Formula |
C29H38FN3O5. HBr
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| Exact mass |
607.2057
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| Mol weight |
608.5395
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| Structure |
     |
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| Activity |
Treatment of cardiovascular disorders
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| Target |
coagulation factor II (thrombin) receptor (PAR1) antagonist [HSA: 2149] [KO: K03914] |
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| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction
hsa04610 Complement and coagulation cascades | |
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| Brite |
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Thrombin
coagulation factor II (thrombin) receptor (PAR1) [HSA:2149] [KO:K03914]
Atopaxar
D09867 Atopaxar hydrobromide (USAN)
 |
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| Other DBs |
CAS: 474550-69-1 PubChem: LigandBox: |
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| KCF data |
ATOM 39
1 C8y C 23.0300 -26.6700
2 C8y C 23.0300 -28.0700
3 C8x C 24.2200 -28.7700
4 C8y C 25.4800 -28.0700
5 C8y C 25.4800 -26.6700
6 C8y C 24.2200 -25.9700
7 C1x C 26.8100 -28.4900
8 N1y N 27.6500 -27.3700
9 C2y C 26.8100 -26.1800
10 C1b C 28.9800 -27.3700
11 X F 24.2200 -24.5000
12 O2a O 21.7700 -25.9700
13 C1b C 20.5800 -26.6000
14 C1a C 19.3900 -25.9700
15 O2a O 21.7700 -28.7700
16 C1b C 20.5800 -28.0700
17 C1a C 19.3900 -28.7700
18 N2a N 27.2300 -24.8500
19 C5a C 29.6800 -28.5600
20 C8y C 31.0800 -28.5600
21 O5a O 28.9800 -29.7500
22 C8x C 31.7800 -29.7500
23 C8y C 33.1800 -29.7500
24 C8y C 33.9500 -28.5600
25 C8y C 33.2500 -27.3700
26 C8x C 31.7800 -27.3700
27 N1y N 33.8800 -30.9400
28 C1x C 33.2500 -32.1300
29 C1x C 33.9500 -33.3900
30 O2x O 35.3500 -33.3900
31 C1x C 36.0500 -32.2000
32 C1x C 35.2800 -30.9400
33 C1d C 33.9500 -26.1100
34 O2a O 35.3500 -28.5600
35 C1a C 36.0500 -29.7500
36 C1a C 35.3500 -26.1100
37 C1a C 33.2500 -24.9200
38 C1a C 34.6500 -24.9200
39 X Br 24.9200 -32.2000
BOND 41
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 5 9 1
11 8 10 1
12 6 11 1
13 1 12 1
14 12 13 1
15 13 14 1
16 2 15 1
17 15 16 1
18 16 17 1
19 9 18 2
20 10 19 1
21 19 20 1
22 19 21 2
23 20 22 1
24 22 23 2
25 23 24 1
26 24 25 2
27 25 26 1
28 20 26 2
29 23 27 1
30 27 28 1
31 28 29 1
32 29 30 1
33 30 31 1
34 31 32 1
35 27 32 1
36 25 33 1
37 24 34 1
38 34 35 1
39 33 36 1
40 33 37 1
41 33 38 1
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