KEGG   DRUG: D10032Help
Entry
D10032                      Drug                                   

Name
Tylvalosin (USAN/INN)
Formula
C53H87NO19
Exact mass
1041.5872
Mol weight
1042.2532
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Veterinary antibacterial
Comment
Tylosin [DR:D02490] derivertive
Target
23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor [KO:K01980]
  Pathway
ko03010  Ribosome  
 
Brite
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   23S rRNA of 50S ribosomal subunit inhibitor
    Macrolides
     Tylvalosin; Veterinary
      D10032  Tylvalosin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
63409-12-1
PubChem: 
LigandBox: 
KCF data Show

ATOM        73
            1   C2x C    14.1699  -11.6135
            2   C2x C    14.1699  -13.0035
            3   C1x C    16.6023  -13.0035
            4   C1y C    16.6023  -11.6135
            5   C5x C    15.3514  -10.9185
            6   C1y C    16.6023  -15.7834
            7   C1y C    17.7838  -15.0884
            8   C1y C    17.7838  -13.6985
            9   C2y C    12.9884  -13.6985
            10  C2x C    12.9884  -15.0884
            11  C7x C    14.1699  -17.1734
            12  C1x C    15.3514  -17.8684
            13  C1y C    16.6023  -17.1734
            14  C1y C    11.6680  -15.7834
            15  C1y C    11.6680  -17.1734
            16  O7x O    12.9884  -17.8684
            17  O6a O    14.1699  -15.7834
            18  O2a O    19.6603  -16.1309
            19  C1b C    18.9653  -13.0035
            20  C4a C    20.1468  -13.6985
            21  O4a O    21.3282  -13.0035
            22  C1a C    17.7838  -10.9185
            23  O5x O    15.3514   -9.5286
            24  C1a C    11.7375  -13.0035
            25  C1b C    10.4865  -15.0884
            26  O2a O     9.2355  -15.7834
            27  C1y C     8.0540  -15.0189
            28  O2x O     8.0540  -13.6290
            29  C1y C     6.8726  -12.9340
            30  C1y C     5.6216  -13.6290
            31  C1y C     5.6216  -15.0189
            32  C1y C     6.8726  -15.7139
            33  C1b C    10.4865  -17.8684
            34  C1a C     9.3050  -17.1734
            35  C1a C    15.4209  -15.0884
            36  C1a C     6.8726  -11.5440
            37  O1a O     4.4401  -12.9340
            38  O2a O     4.4401  -15.7139
            39  C1a C     3.2587  -15.0189
            40  O2a O     6.8726  -17.1039
            41  C1a C     5.6911  -17.7989
            42  C1y C    20.8417  -16.8259
            43  C1y C    20.8417  -18.2159
            44  C1y C    22.0232  -18.9803
            45  C1y C    23.2742  -18.2159
            46  C1y C    23.2742  -16.8259
            47  O2x O    22.0232  -16.1309
            48  O1a O    19.6603  -18.9803
            49  O2a O    24.4557  -18.9803
            50  C1a C    24.4557  -16.1309
            51  N1c N    22.0232  -20.3703
            52  C1a C    20.8417  -21.0653
            53  C1a C    23.2047  -21.0653
            54  C1y C    25.7066  -19.6753
            55  C1x C    25.7066  -21.0653
            56  C1z C    26.8881  -21.7603
            57  C1y C    28.0696  -21.0653
            58  C1y C    28.0696  -19.6753
            59  O2x O    26.8881  -18.9803
            60  C1a C    29.2510  -18.9803
            61  C1a C    27.8611  -22.7332
            62  O1a O    26.0541  -22.8722
            63  O7a O    29.2510  -21.7603
            64  C7a C    30.4604  -21.0751
            65  C1b C    31.6333  -21.7652
            66  O6a O    30.4725  -19.6759
            67  C1c C    32.8301  -21.0871
            68  C1a C    33.9929  -21.7711
            69  C1a C    32.7725  -19.6761
            70  O7a O    17.8003  -17.8783
            71  C7a C    17.8003  -19.2683
            72  C1a C    16.5886  -19.9679
            73  O6a O    18.9874  -19.9535
BOND        76
            1     1   2 2
            2     3   4 1
            3     4   5 1
            4     1   5 1
            5     6   7 1
            6     7   8 1
            7     3   8 1
            8     2   9 1
            9     9  10 2
            10   11  12 1
            11   12  13 1
            12   13   6 1
            13   10  14 1
            14   14  15 1
            15   15  16 1
            16   11  16 1
            17   11  17 2
            18    7  18 1 #Down
            19    8  19 1 #Down
            20   19  20 1
            21   20  21 2
            22    4  22 1 #Down
            23    5  23 2
            24    9  24 1
            25   14  25 1 #Up
            26   25  26 1
            27   27  26 1 #Up
            28   27  28 1
            29   28  29 1
            30   29  30 1
            31   30  31 1
            32   31  32 1
            33   27  32 1
            34   15  33 1 #Down
            35   33  34 1
            36    6  35 1 #Down
            37   29  36 1 #Up
            38   30  37 1 #Down
            39   31  38 1 #Down
            40   38  39 1
            41   32  40 1 #Down
            42   40  41 1
            43   42  43 1
            44   43  44 1
            45   44  45 1
            46   45  46 1
            47   46  47 1
            48   42  47 1
            49   43  48 1 #Up
            50   45  49 1 #Up
            51   46  50 1 #Down
            52   42  18 1 #Down
            53   44  51 1 #Down
            54   51  52 1
            55   51  53 1
            56   54  49 1 #Down
            57   54  55 1
            58   55  56 1
            59   56  57 1
            60   57  58 1
            61   58  59 1
            62   54  59 1
            63   58  60 1 #Up
            64   56  61 1 #Up
            65   56  62 1 #Down
            66   57  63 1 #Down
            67   63  64 1
            68   64  65 1
            69   64  66 2
            70   65  67 1
            71   67  68 1
            72   67  69 1
            73   13  70 1 #Down
            74   70  71 1
            75   71  72 1
            76   71  73 2

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