KEGG   DRUG: D10078Help
Entry
D10078                      Drug                                   

Name
Peginterferon lambda-1a (USAN)
Formula
C875H1408N254O251S5(C2H4O)n
Structure
Mol fileKCF fileDB searchJmolKegDraw
Sequence
*MKPTTTGKGC HIGRFKSLSP QELASFKKAR DALEESLKLK NWSCSSPVFP GNWDLRLLQV
RERPVALEAE LALTLKVLEA AAGPALEDVL DQPLHTLHHI LSQLQACIQP QPTAGPRPRG
RLHHWLHRLQ EAPKKESAGC LEASVTFNLF RLLTRDLKYV ADGNLSLRTS THPEST
(*M=modified residue)
  Type
Peptide
Activity
Treatment of chronic hepatitis C infection
Target
interleukin 28 receptor, alpha agonist [HSA:163702] [KO:K05140]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class II cytokine receptors (interferon/IL-10 family receptors)
   interleukin 28 receptor, alpha
    Peginterferon lambda-1a
     D10078  Peginterferon lambda-1a (USAN)
BRITE hierarchy
Other DBs
PubChem: 
KCF data Show

ATOM        17
            1   O2a O     9.2400  -17.5000
            2   C1b C    10.4524  -18.2000
            3   C1a C     7.5376  -18.3400
            4   C1b C    11.6479  -17.5096
            5   O2a O    12.8353  -18.1951
            6   C1b C    14.0265  -17.5071
            7   C1b C    15.2160  -18.1938
            8   C1b C    16.4061  -17.5065
            9   N1b N    17.5962  -18.1935
            10  C1c C    18.7860  -17.5063
            11  C4a C    19.9762  -18.1934
            12  Z   *    21.1660  -17.5062
            13  O4a O    19.9765  -19.5997
            14  C1b C    18.7860  -16.1002
            15  C1b C    17.5541  -15.3888
            16  S2a S    16.3488  -16.0846
            17  C1a C    15.1665  -15.4018
BOND        16
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     7   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   11  13 2
            13   10  14 1 #Up
            14   14  15 1
            15   15  16 1
            16   16  17 1
BRACKET     1     8.6100  -19.5300    8.6100  -16.3100
            1    11.7600  -16.3100   11.7600  -19.5300
            1  n
 ORIGINAL  1    1   2   4
 REPEAT    1

» Japanese version   » Back

DBGET integrated database retrieval system