KEGG   DRUG: Amitifadine hydrochlorideHelp
Entry
D10089                      Drug                                   

Name
Amitifadine hydrochloride (USAN)
Formula
C11H11Cl2N. HCl
Exact mass
263.0035
Mol weight
264.5787
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Remark
Chemical structure group: DG01386
Efficacy
Antidepressant
Comment
Treatment of depression
Target
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
Brite
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (noradrenalin transporter)
     Amitifadine
      D10089  Amitifadine hydrochloride (USAN)
    SLC6A3 (dopamine transporter)
     Amitifadine
      D10089  Amitifadine hydrochloride (USAN)
    SLC6A4 (serotonin transporter)
     Amitifadine
      D10089  Amitifadine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 410074-74-7
PubChem: 135626808
ChEMBL: CHEMBL1818442
LigandBox: D10089
KCF data Show

ATOM        15
            1   C8x C    27.0200  -20.8600
            2   C8y C    27.0200  -22.2600
            3   C8y C    25.8300  -22.9600
            4   C8x C    24.5700  -22.2600
            5   C8y C    24.5700  -20.8600
            6   C8x C    25.8300  -20.1600
            7   X   Cl   25.8300  -24.3600
            8   X   Cl   28.2100  -22.9600
            9   C1z C    23.3800  -20.1600
            10  C1y C    21.9800  -20.1600
            11  C1x C    22.6800  -21.3500
            12  C1x C    23.8000  -18.8300
            13  N1x N    22.6800  -17.9900
            14  C1x C    21.4900  -18.8300
            15  X   Cl   28.3500  -18.2700
BOND        16
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     3   7 1
            8     2   8 1
            9     9   5 1 #Up
            10    9  10 1
            11   10  11 1
            12   11   9 1
            13    9  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1

» Japanese version   » Back

DBGET integrated database retrieval system