KEGG   DRUG: D10112Help
Entry
D10112                      Drug                                   

Name
Dexmecamylamine hydrochloride (USAN)
Formula
C11H21N. HCl
Exact mass
203.1441
Mol weight
203.7521
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of major depressive disorder
Target
nicotinic cholinergic receptor alpha4beta2 antagonist [HSA:1137 1141] [KO:K04806 K04813]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   Acetylcholine (nicotinic)
    alpha4beta2 nicotinic receptor
     Dexmecamylamine
      D10112  Dexmecamylamine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
107596-30-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        13
            1   C1z C    25.1300  -20.5100
            2   C1y C    23.9400  -19.8100
            3   C1z C    25.1300  -21.9100
            4   C1x C    23.4500  -21.1400
            5   C1x C    22.6800  -20.5100
            6   C1y C    23.9400  -22.5400
            7   C1x C    22.6800  -21.9100
            8   C1a C    26.3200  -19.8100
            9   C1a C    26.3200  -22.6100
            10  C1a C    25.1300  -23.3100
            11  N1b N    25.1300  -19.1100
            12  C1a C    26.3200  -18.4100
            13  X   Cl   29.6800  -21.5600
BOND        13
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     2   5 1 #Up
            5     3   6 1
            6     5   7 1
            7     6   4 1
            8     6   7 1 #Up
            9     1   8 1 #Up
            10    3   9 1
            11    3  10 1
            12    1  11 1 #Down
            13   11  12 1

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