| Entry |
|
|---|
| Name |
Levomilnacipran hydrochloride (USAN);
Fetzima (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C15H22N2O. HCl
|
|---|
| Exact mass |
282.1499
|
|---|
| Mol weight |
282.8089
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Remark |
| Product (DG01387): | D10133<US> |
|
|---|
| Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
|---|
| Disease |
Major depressive disorder [DS: H01646] |
|---|
| Comment |
selective serotonin norepinephrine reuptake inhibitor (SNRI)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX28 Levomilnacipran
D10133 Levomilnacipran hydrochloride (USAN) <US>
USP drug classification [BR:br08302]
Antidepressants
SSRIs/SNRIs (Selective Serotonin Reuptake Inhibitors/Serotonin and Norepinephrine Reuptake Inhibitors)
Levomilnacipran
D10133 Levomilnacipran hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D10133 Levomilnacipran hydrochloride (USAN) <US>
SLC6A4 (HTT)
D10133 Levomilnacipran hydrochloride (USAN) <US>
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 C8x C 20.8600 -18.9700
2 C8x C 20.8600 -20.3700
3 C8x C 22.0500 -21.0700
4 C8y C 23.3100 -20.3700
5 C8x C 23.3100 -18.9700
6 C8x C 22.0500 -18.2700
7 C5a C 24.7100 -20.3700
8 C1x C 23.3100 -22.8200
9 C1y C 24.7100 -22.8200
10 C1z C 24.0100 -21.5600
11 C1b C 25.4100 -24.0100
12 O5a O 24.7100 -18.9700
13 N1c N 26.1100 -20.3700
14 C1b C 26.8100 -19.1800
15 C1b C 26.8100 -21.5600
16 C1a C 28.2100 -21.5600
17 C1a C 28.2100 -19.1800
18 N1a N 26.8100 -24.0100
19 X Cl 31.6400 -24.0100
BOND 19
1 8 10 1
2 10 9 1
3 3 4 2
4 9 11 1 #Down
5 10 4 1 #Up
6 10 7 1 #Down
7 4 5 1
8 7 12 2
9 5 6 2
10 7 13 1
11 6 1 1
12 13 14 1
13 13 15 1
14 15 16 1
15 1 2 2
16 14 17 1
17 2 3 1
18 11 18 1
19 8 9 1
|
|---|
