KEGG   DRUG: PlazomicinHelp
Entry
D10151                      Drug                                   

Name
Plazomicin (USAN)
Formula
C25H48N6O10
Exact mass
592.3432
Mol weight
592.6828
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Chemical structure group: DG01833
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Drug interaction
Other DBs
CAS: 1154757-24-0
PubChem: 135626869
ChEMBL: CHEMBL1650559
PDB-CCD: EDS[PDBj]
LigandBox: D10151
KCF data Show

ATOM        41
            1   C1x C    18.3400  -25.8300
            2   C1z C    18.3400  -27.2300
            3   C1y C    19.5524  -27.9300
            4   C1y C    20.7649  -27.2300
            5   C1y C    20.7649  -25.8300
            6   O2x O    19.5524  -25.1300
            7   O2a O    21.9960  -25.1190
            8   O1a O    21.9960  -27.9410
            9   N1b N    19.5524  -29.3298
            10  O1a O    16.9400  -27.2300
            11  C1a C    17.6400  -28.4424
            12  C1a C    18.3232  -30.0397
            13  C1y C    23.2084  -24.4190
            14  C1y C    24.4492  -25.1355
            15  C1x C    25.6617  -24.4356
            16  C1y C    25.6619  -23.0356
            17  C1y C    24.4211  -22.3191
            18  C1y C    23.2086  -23.0190
            19  N1b N    24.4490  -26.5299
            20  O1a O    22.0246  -22.3351
            21  N1a N    26.8978  -22.3220
            22  C5a C    25.6471  -27.2219
            23  C1c C    26.8358  -26.5358
            24  O5a O    25.6470  -28.6297
            25  C1b C    28.0262  -27.2234
            26  O1a O    26.8361  -25.1302
            27  C1b C    29.2162  -26.5366
            28  N1a N    30.4060  -27.2238
            29  O2a O    24.4213  -20.9300
            30  C1y C    25.6404  -20.2264
            31  O2x O    26.8389  -20.9188
            32  C2y C    28.0515  -20.2191
            33  C2x C    28.0518  -18.8191
            34  C1x C    26.8533  -18.1267
            35  C1y C    25.6407  -18.8264
            36  N1a N    24.4146  -18.1180
            37  C1b C    29.2824  -20.9301
            38  N1b N    29.2821  -22.3298
            39  C1b C    30.4778  -23.0206
            40  C1b C    31.6654  -22.3352
            41  O1a O    32.8563  -23.0232
BOND        43
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     4   8 1 #Down
            9     3   9 1 #Up
            10    2  10 1 #Up
            11    2  11 1 #Down
            12    9  12 1
            13   13   7 1 #Down
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   13  18 1
            20   14  19 1 #Up
            21   18  20 1 #Up
            22   16  21 1 #Up
            23   19  22 1
            24   22  23 1
            25   22  24 2
            26   23  25 1
            27   23  26 1 #Up
            28   25  27 1
            29   27  28 1
            30   17  29 1 #Down
            31   30  29 1 #Down
            32   30  31 1
            33   31  32 1
            34   32  33 2
            35   33  34 1
            36   34  35 1
            37   30  35 1
            38   35  36 1 #Down
            39   32  37 1
            40   37  38 1
            41   38  39 1
            42   39  40 1
            43   40  41 1

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